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Impact and effectiveness of the quadrivalent human papillomavirus vaccine: A systematic review of 10 years of real-world experience

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dc.creatorGarland, Suzanne M.spa
dc.creatorKjaer, Susanne K.spa
dc.creatorMuñoz, Nubiaspa
dc.creatorBlock, Stan L.spa
dc.creatorBrown, Darron R.spa
dc.creatorDiNubile, Mark J.spa
dc.creatorLindsay, Brianna R.spa
dc.creatorKuter, Barbara J.spa
dc.creatorPerez, Gonzalospa
dc.creatorDominiak-Felden, Geraldinespa
dc.creatorSaah, Alfred J.spa
dc.creatorDrury, Rosybelspa
dc.creatorDas, Rituparnaspa
dc.creatorVelicer, Christinespa
dc.date.accessioned2020-05-26T00:04:28Z
dc.date.available2020-05-26T00:04:28Z
dc.date.created2016spa
dc.description.abstractProphylactic human papillomavirus (HPV) vaccination programs constitute major public health initiatives worldwide. We assessed the global effect of quadrivalent HPV (4vHPV) vaccination on HPV infection and disease. PubMed and Embase were systematically searched for peer-reviewed articles from January 2007 through February 2016 to identify observational studies reporting the impact or effectiveness of 4vHPV vaccination on infection, anogenital warts, and cervical cancer or precancerous lesions. Over the last decade, the impact of HPV vaccination in real-world settings has become increasingly evident, especially among girls vaccinated before HPV exposure in countries with high vaccine uptake. Maximal reductions of approximately 90% for HPV 6/11/16/18 infection, approximately 90% for genital warts, approximately 45% for low-grade cytological cervical abnormalities, and approximately 85% for high-grade histologically proven cervical abnormalities have been reported. The full public health potential of HPV vaccination is not yet realized. HPV-related disease remains a significant source of morbidity and mortality in developing and developed nations, underscoring the need for HPV vaccination programs with high population coverage. © 2016 The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1093/cid/ciw354
dc.identifier.issn15376591
dc.identifier.issn10584838
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23687
dc.language.isoengspa
dc.publisherOxford University Pressspa
dc.relation.citationEndPage527
dc.relation.citationIssueNo. 4
dc.relation.citationStartPage519
dc.relation.citationTitleClinical Infectious Diseases
dc.relation.citationVolumeVol. 63
dc.relation.ispartofClinical Infectious Diseases, ISSN:15376591, 10584838, Vol.63, No.4 (2016); pp. 519-527spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84982168442&doi=10.1093%2fcid%2fciw354&partnerID=40&md5=25c420ed82ce3d6a9ca9cf0c35ec43c9spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordWart virus vaccinespa
dc.subject.keywordWart virus vaccinespa
dc.subject.keywordClinical effectivenessspa
dc.subject.keywordCondyloma acuminatumspa
dc.subject.keywordDrug exposurespa
dc.subject.keywordEmbasespa
dc.subject.keywordHistopathologyspa
dc.subject.keywordHumanspa
dc.subject.keywordHuman papillomavirus type 11spa
dc.subject.keywordHuman papillomavirus type 18spa
dc.subject.keywordHuman papillomavirus type 6spa
dc.subject.keywordMedlinespa
dc.subject.keywordObservational studyspa
dc.subject.keywordPapillomavirus infectionspa
dc.subject.keywordPrecancerspa
dc.subject.keywordPriority journalspa
dc.subject.keywordReviewspa
dc.subject.keywordSystematic reviewspa
dc.subject.keywordUterine cervix cancerspa
dc.subject.keywordUterine cervix cytologyspa
dc.subject.keywordVaccinationspa
dc.subject.keywordCondyloma acuminatumspa
dc.subject.keywordFemalespa
dc.subject.keywordImmunologyspa
dc.subject.keywordMalespa
dc.subject.keywordPapillomaviridaespa
dc.subject.keywordPapillomavirus infectionspa
dc.subject.keywordUterine cervix tumorspa
dc.subject.keywordVaccinationspa
dc.subject.keywordVirologyspa
dc.subject.keywordCondylomata Acuminataspa
dc.subject.keywordFemalespa
dc.subject.keywordHuman Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18spa
dc.subject.keywordHumansspa
dc.subject.keywordMalespa
dc.subject.keywordPapillomaviridaespa
dc.subject.keywordPapillomavirus Infectionsspa
dc.subject.keywordUterine Cervical Neoplasmsspa
dc.subject.keywordVaccinationspa
dc.subject.keywordCervical cancerspa
dc.subject.keywordCINspa
dc.subject.keywordGardasil/Silgardspa
dc.subject.keywordGenital wartsspa
dc.subject.keywordHPV vaccinationspa
dc.titleImpact and effectiveness of the quadrivalent human papillomavirus vaccine: A systematic review of 10 years of real-world experiencespa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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