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From endothelial dysfunction to arterial stiffness in diabetes mellitus

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dc.creatorGiraldo-Grueso, Manuelspa
dc.creatorEcheverri, Daríospa
dc.date.accessioned2020-05-26T00:05:30Z
dc.date.available2020-05-26T00:05:30Z
dc.date.created2020spa
dc.description.abstractPrevalence of diabetes mellitus has increased drastically over time, especially in more populous countries such as the United States, India, and China. Patients with diabetes have an increased risk of major cardiovascular events such as acute myocardial infarction, cerebrovascular dis-ease, and peripheral vascular disease. Arterial stiffness is a process related to aging and vascular, metabolic, cellular and physiological deterioration. In recent years, it has been described as an independent predictor of cardiovascular mortality and coronary artery disease. Additionally, it plays an important role in the measurement of chronic disease progression. Recent studies have suggested a strong relationship between diabetes mellitus and arterial stiffness since they share a similar pathophysiology involving endothelial dysfunction. The literature has shown that microvascular and mac-rovascular complications in diabetic patients could be screened and measured with arterial stiffness. Additionally, new evidence proposes that there is a relationship between blood glucose levels, micro-albuminuria, and arterial stiffness. Moreover, arterial stiffness predicts cardiovascular risk and is in-dependently associated with mortality in diabetic patients. Abnormal arterial stiffness values in diabetic patients should alert the clinician to the presence of vascular disease, which merits early study and treatment. We await more studies to determine if arterial stiffness could be considered a routine useful non-invasive tool in the evaluation of diabetic patients. There is enough evidence to conclude that arterial stiffness is related to the progression of diabetes mellitus. © 2020 Bentham Science Publishers.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.2174/1573399814666181017120415
dc.identifier.issn15733998
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23800
dc.language.isoengspa
dc.publisherBentham Science Publishersspa
dc.relation.citationEndPage237
dc.relation.citationIssueNo. 3
dc.relation.citationStartPage230
dc.relation.citationTitleCurrent Diabetes Reviews
dc.relation.citationVolumeVol. 16
dc.relation.ispartofCurrent Diabetes Reviews, ISSN:15733998, Vol.16, No.3 (2020); pp. 230-237spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85082492629&doi=10.2174%2f1573399814666181017120415&partnerID=40&md5=c0022b5846dc14162a4f07a0d52fede6spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordArterial stiffnessspa
dc.subject.keywordvasculareng
dc.subject.keywordAtherosclerosisspa
dc.subject.keywordAtherosclerotic plaquespa
dc.subject.keywordCardiovascular riskspa
dc.subject.keywordDiabetes mellitusspa
dc.subject.keywordDiabetic patientspa
dc.subject.keywordEndothelial dysfunctionspa
dc.subject.keywordGlucose blood levelspa
dc.subject.keywordHumanspa
dc.subject.keywordImpaired glucose tolerancespa
dc.subject.keywordInflammationspa
dc.subject.keywordInsulin dependent diabetes mellitusspa
dc.subject.keywordMicroalbuminuriaspa
dc.subject.keywordMortalityspa
dc.subject.keywordNon insulin dependent diabetes mellitusspa
dc.subject.keywordOxidative stressspa
dc.subject.keywordPathophysiologyspa
dc.subject.keywordPredictive valuespa
dc.subject.keywordPriority journalspa
dc.subject.keywordProtein glycosylationspa
dc.subject.keywordThrombocyte functionspa
dc.subject.keywordVascular diseasespa
dc.subject.keywordArterial stiffnessspa
dc.subject.keywordDiabetes mellitusspa
dc.subject.keywordDiabetic angiopathyspa
dc.subject.keywordDisease exacerbationspa
dc.subject.keywordPathophysiologyspa
dc.subject.keywordPhysiologyspa
dc.subject.keywordRisk factorspa
dc.subject.keywordVascular endotheliumspa
dc.subject.keywordDiabetes mellitusspa
dc.subject.keywordDiabetic angiopathiesspa
dc.subject.keywordDisease progressionspa
dc.subject.keywordEndotheliumeng
dc.subject.keywordHumansspa
dc.subject.keywordRisk factorsspa
dc.subject.keywordVascular stiffnessspa
dc.subject.keywordCoronary heart diseasespa
dc.subject.keywordDiabetes mellitusspa
dc.subject.keywordDiabetic angiopathiesspa
dc.subject.keywordDiabetic neuropathiesspa
dc.subject.keywordDiabetic retinopathyspa
dc.subject.keywordVascular stiffnessspa
dc.titleFrom endothelial dysfunction to arterial stiffness in diabetes mellitusspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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