Ítem
Acceso Abierto
The autoimmune tautology
| dc.creator | Anaya, Juan-Manuel | |
| dc.creator.google | Anaya, Juan-Manuel | spa |
| dc.date.accessioned | 2020-05-07T15:04:14Z | |
| dc.date.available | 2020-05-07T15:04:14Z | |
| dc.date.created | 2010 | |
| dc.date.issued | 2010 | |
| dc.description.abstract | Although autoimmune diseases exhibit contrasting epidemiological features, pathology, and clinical manifestations, three lines of evidence demonstrate that these diseases share similar immunogenetic mechanisms (that is, autoimmune tautology). First, clinical evidence highlights the co-occurrence of distinct autoimmune diseases within an individual (that is, polyautoimmunity) and within members of a nuclear family (that is, familial autoimmunity). Second, physiopathologic evidence indicates that the pathologic mechanisms may be similar among autoimmune diseases. Lastly, genetic evidence shows that autoimmune phenotypes might represent pleiotropic outcomes of the interaction of non-specific disease genes. © 2010 BioMed Central Ltd. | eng |
| dc.format.mimetype | application/pdf | |
| dc.identifier.doi | https://doi.org/10.1186/ar3175 | |
| dc.identifier.issn | 1478-6354 | |
| dc.identifier.uri | https://repository.urosario.edu.co/handle/10336/21895 | |
| dc.language.iso | eng | spa |
| dc.relation.citationIssue | No. 6 | |
| dc.relation.citationTitle | Arthritis Research and Therapy | |
| dc.relation.citationVolume | Vol. 12 | |
| dc.relation.ispartof | Arthritis Research and Therapy, ISSN: 1478-6354 Vol. 12, No. 6 (2010) | spa |
| dc.relation.uri | https://arthritis-research.biomedcentral.com/track/pdf/10.1186/ar3175 | spa |
| dc.rights.accesRights | info:eu-repo/semantics/openAccess | |
| dc.rights.acceso | Abierto (Texto Completo) | spa |
| dc.source.instname | instname:Universidad del Rosario | |
| dc.source.reponame | reponame:Repositorio Institucional EdocUR | |
| dc.subject.ddc | Enfermedades | spa |
| dc.subject.keyword | Autoimmunity | spa |
| dc.subject.keyword | Editorial | spa |
| dc.subject.keyword | Genetic risk | spa |
| dc.subject.keyword | Genetic susceptibility | spa |
| dc.subject.keyword | Immunogenetics | spa |
| dc.subject.keyword | Autoimmune disease | spa |
| dc.title | The autoimmune tautology | spa |
| dc.type | other | eng |
| dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | |
| dc.type.spa | Editorial | spa |
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