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Prevalence and clinical features of multiple sclerosis in Latin America

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dc.creatorOjeda, Ernestospa
dc.creatorDíaz-Cortes, Dianaspa
dc.creatorRosales, Dominiquespa
dc.creatorDuarte-Rey, Carolina
dc.creatorAnaya, Juan-Manuelspa
dc.creatorRojas-Villarraga, Adriana
dc.date.accessioned2020-05-26T00:04:29Z
dc.date.available2020-05-26T00:04:29Z
dc.date.created2013spa
dc.description.abstractMultiple sclerosis (MS) in Latin America (LA) is considered to have a low to medium prevalence. However, accurate information on MS in LA is scarce. The aim of this study was to compare clinical characteristics among LA patients through a systematic review of the literature. A systematic search (Spanish, Portuguese and English) was done for all clinical studies of MS in humans (MEDLINE, PubMed, Scielo, BIREME, EMBASE and LILACS) up to May 2011 being focused on a well-defined Latin American population (peer-reviewed journal) following the MOOSE guidelines. The search strategy included combinations of different Mesh terms (two independent researchers). Classification of each article by using the Oxford Centre for Evidence-based Medicine-Levels of Evidence was done. The total number of patients per country for each specific characteristic was compiled. Chi-square test was used to compare the characteristics in the studies retrieved per country. There were 38 articles fulfilling the inclusion criteria, accounting for 4524 patients. Relapsing-remitting form was the most frequent in LA patients and the main initial symptom was motor, followed by optic neuritis and sensorial. A mild expanded disability status scale was the most prevalent in all LA countries. Factors accounting for differences in distribution and clinical course across LA countries include genetics, environment, diagnostic techniques, socioeconomic structure and medical facilities. © 2012 Elsevier B.V.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.clineuro.2012.11.028
dc.identifier.issn3038467
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23688
dc.language.isoengspa
dc.relation.citationEndPage387
dc.relation.citationIssueNo. 4
dc.relation.citationStartPage381
dc.relation.citationTitleClinical Neurology and Neurosurgery
dc.relation.citationVolumeVol. 115
dc.relation.ispartofClinical Neurology and Neurosurgery, ISSN:3038467, Vol.115, No.4 (2013); pp. 381-387spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84875216641&doi=10.1016%2fj.clineuro.2012.11.028&partnerID=40&md5=841cdf9bfb9d6bee442ecbcbb3bbd5abspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordClinical featurespa
dc.subject.keywordchronic progressiveeng
dc.subject.keywordDisabilityspa
dc.subject.keywordDisease severityspa
dc.subject.keywordEthnicityspa
dc.subject.keywordHumanspa
dc.subject.keywordMotor dysfunctionspa
dc.subject.keywordMultiple sclerosisspa
dc.subject.keywordOptic neuritisspa
dc.subject.keywordPrevalencespa
dc.subject.keywordRelapsespa
dc.subject.keywordReviewspa
dc.subject.keywordSocial statusspa
dc.subject.keywordSouth and central americaspa
dc.subject.keywordSystematic reviewspa
dc.subject.keywordAdultspa
dc.subject.keywordAge of onsetspa
dc.subject.keywordChi-square distributionspa
dc.subject.keywordColombiaspa
dc.subject.keywordDisability evaluationspa
dc.subject.keywordFemalespa
dc.subject.keywordHumansspa
dc.subject.keywordLatin americaspa
dc.subject.keywordMalespa
dc.subject.keywordMiddle agedspa
dc.subject.keywordMultiple sclerosisspa
dc.subject.keywordMultiple sclerosiseng
dc.subject.keywordPrevalencespa
dc.subject.keywordSocioeconomic factorsspa
dc.subject.keywordEpidemiologyspa
dc.subject.keywordLatin americaspa
dc.subject.keywordMultiple sclerosisspa
dc.subject.keywordPrevalencespa
dc.titlePrevalence and clinical features of multiple sclerosis in Latin Americaspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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