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A latitudinal gradient study of common anti-infectious agent antibody prevalence in Italy and Colombia

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dc.creatorPordeus V.spa
dc.creatorBarzilai O.spa
dc.creatorSherer Y.spa
dc.creatorLuiz R.R.spa
dc.creatorBlank M.spa
dc.creatorBizzaro N.spa
dc.creatorVillalta D.spa
dc.creatorAnaya, Juan-Manuelspa
dc.creatorShoenfeld Y.spa
dc.date.accessioned2020-05-25T23:55:44Z
dc.date.available2020-05-25T23:55:44Z
dc.date.created2008spa
dc.description.abstractBackground: Infectious agents are important in the pathogenesis of autoimmune disease since they are a major part of the environmental trigger of autoimmunity. A negative relationship between latitude and infectious disease species richness has been suggested. Objectives: To examine whether their prevalence differs in two latitudinally different populations. Methods: The prevalence of infections with Toxoplasma gondii, rubella virus, cytomegalovirus, Epstein-Barr virus and Treponema pallidum was compared between subjects from Italy and Colombia. Results: We found high titers of antibodies against four of five microorganisms tested, Toxoplasma gondii (50.8%), rubella virus (German measles) (75%), cytomegalovirus (86.3%), Epstein-Barr virus (83.3%) and Treponema pallidum (6.3%) in completely healthy individuals from a tropical country (Colombia) and a European country (Italy). Differences between two groups of volunteers were noted regarding two infectious agents. The prevalence of immunoglobulin G anti-rubella antibodies was significantly higher among Italian subjects (85% vs. 67.9%, P = 0.002), whereas antibodies against CMV were less prevalent among Italian as compared to Colombian subjects (77% vs. 92.9%, P less than 0.001). Conclusions: These differences might also result in a different tendency towards development of autoimmune diseases associated with these infectious agents in different populations.eng
dc.format.mimetypeapplication/pdf
dc.identifier.issn15651088
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/22195
dc.language.isoengspa
dc.relation.citationEndPage68
dc.relation.citationIssueNo. 1
dc.relation.citationStartPage65
dc.relation.citationTitleIsrael Medical Association Journal
dc.relation.citationVolumeVol. 10
dc.relation.ispartofIsrael Medical Association Journal, ISSN:15651088, Vol.10, No.1 (2008); pp. 65-68spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-41149158618&partnerID=40&md5=963cab26e8b86876d402f1d5ddccdb0cspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordBacterium antibodyspa
dc.subject.keywordhumaneng
dc.subject.keywordCytomegalovirus antibodyspa
dc.subject.keywordImmunoglobulin gspa
dc.subject.keywordProtozoon antibodyspa
dc.subject.keywordRubella antibodyspa
dc.subject.keywordVirus antibodyspa
dc.subject.keywordAntibodyspa
dc.subject.keywordImmunoglobulin gspa
dc.subject.keywordAdultspa
dc.subject.keywordAntibody titerspa
dc.subject.keywordArticlespa
dc.subject.keywordAutoimmune diseasespa
dc.subject.keywordAutoimmunityspa
dc.subject.keywordBacterial infectionspa
dc.subject.keywordColombiaspa
dc.subject.keywordControlled studyspa
dc.subject.keywordCytomegalovirusspa
dc.subject.keywordCytomegalovirus infectionspa
dc.subject.keywordDisease associationspa
dc.subject.keywordEpstein barr virusspa
dc.subject.keywordFemalespa
dc.subject.keywordHumanspa
dc.subject.keywordImmunoassayspa
dc.subject.keywordItalyspa
dc.subject.keywordLatitudespa
dc.subject.keywordMalespa
dc.subject.keywordNormal humanspa
dc.subject.keywordPathogenesisspa
dc.subject.keywordPrevalencespa
dc.subject.keywordRace differencespa
dc.subject.keywordRubellaspa
dc.subject.keywordRubella virusspa
dc.subject.keywordSpecies diversityspa
dc.subject.keywordToxoplasma gondiispa
dc.subject.keywordToxoplasmosisspa
dc.subject.keywordTreponema pallidumspa
dc.subject.keywordVirus infectionspa
dc.subject.keywordVolunteerspa
dc.subject.keywordAdolescentspa
dc.subject.keywordAnimalspa
dc.subject.keywordBloodspa
dc.subject.keywordComparative studyspa
dc.subject.keywordImmunologyspa
dc.subject.keywordMiddle agedspa
dc.subject.keywordToxoplasmaspa
dc.subject.keywordAdolescentspa
dc.subject.keywordAdultspa
dc.subject.keywordAnimalsspa
dc.subject.keywordAntibodiesspa
dc.subject.keywordColombiaspa
dc.subject.keywordCytomegalovirusspa
dc.subject.keywordFemalespa
dc.subject.keywordHerpesvirus 4eng
dc.subject.keywordHumansspa
dc.subject.keywordImmunoglobulin gspa
dc.subject.keywordItalyspa
dc.subject.keywordMalespa
dc.subject.keywordMiddle agedspa
dc.subject.keywordRubella virusspa
dc.subject.keywordToxoplasmaspa
dc.subject.keywordTreponema pallidumspa
dc.subject.keywordCytomegalovirusspa
dc.subject.keywordEpstein-barr virusspa
dc.subject.keywordRubella virusspa
dc.subject.keywordToxoplasma gondiispa
dc.subject.keywordTreporema pallidumspa
dc.titleA latitudinal gradient study of common anti-infectious agent antibody prevalence in Italy and Colombiaspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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