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Chronic intrathecal baclofen administration in severe spasticity

dc.creatorBroseta, J.spa
dc.creatorGarcia-March, G.spa
dc.creatorSánchez-Ledesma, M.J.spa
dc.creatorAnaya, Juan-Manuelspa
dc.creatorSilva, I.spa
dc.date.accessioned2020-08-19T14:41:54Z
dc.date.available2020-08-19T14:41:54Z
dc.date.created1990-11-28spa
dc.description.abstractOn the basis of previous experimental and clinical studies, 14 patients with severe spasticity due to central or spinal cord damage, resistant to all conservative treatments, were selected after a percutaneous trial period for chronic intrathecal baclofen infusion by programmable pumps. The agent was delivered at C4 in quadriplegic patients or in cases with central spasticity and in the neighbouring areas on the affected segments in paraplegic patients. The daily baclofen dose varied from 25 to 260 µg and was infused in a bolus, continuously infused or both combined according to the results during the trial period. After a mean follow-up period of 11 months, constant decrease of rigidity, absence of spasms, improvement of bladder function, cramping pain remission, and moderate improvement in walking capacity and transfer activities were usually observed. Neither complications nor side effects were noted.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1159/000100205
dc.identifier.issnISSN: 1011-6125
dc.identifier.issnEISSN: 1423-0372
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/27366
dc.language.isoengspa
dc.publisherKarger AGspa
dc.relation.citationEndPage153
dc.relation.citationIssueNo. 1-8
dc.relation.citationStartPage147
dc.relation.citationTitleStereotactic and Functional Neurosurgery
dc.relation.citationVolumeVol. 54-55
dc.relation.ispartofStereotactic and Functional Neurosurgery, ISSN: 1011-6125;EISSN: 1423-0372, Vol.54-55, No.1-8 (1990); pp. 147-153spa
dc.relation.urihttps://www.karger.com/Article/Abstract/100205spa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourceStereotactic and Functional Neurosurgeryspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordBaclofenspa
dc.subject.keywordSpasticityspa
dc.subject.keywordProgrammable pumpsspa
dc.subject.keywordSpinal infusionspa
dc.titleChronic intrathecal baclofen administration in severe spasticityspa
dc.title.TranslatedTitleAdministración crónica de baclofeno intratecal en espasticidad severaspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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