Ítem
Solo Metadatos

Guillain-Barré syndrome: causes, immunopathogenic mechanisms and treatment

Mostrar el registro sencillo de la publicación
dc.creatorJasti, Anil Kspa
dc.creatorSelmi, Carlospa
dc.creatorSarmiento-Monroy, Juan Cspa
dc.creatorVega, Daniel Aspa
dc.creatorAnaya, Juan-Manuelspa
dc.creatorGershwin, M Ericspa
dc.date.accessioned2020-05-26T00:07:56Z
dc.date.available2020-05-26T00:07:56Z
dc.date.created2016spa
dc.description.abstractIntroduction: Guillain-Barré syndrome is a rare disease representing the most frequent cause of acute flaccid symmetrical weakness of the limbs and areflexia usually reaching its peak within a month. The etiology and pathogenesis remain largely enigmatic and the syndrome results in death or severe disability in 9–17% of cases despite immunotherapy. Areas covered: In terms of etiology, Guillain-Barré syndrome is linked to Campylobacter infection but less than 0.1% of infections result in the syndrome. In terms of pathogenesis, activated macrophages and T cells and serum antibodies against gangliosides are observed but their significance is unclear. Expert commentary: Guillain-Barré syndrome is a heterogeneous condition with numerous subtypes and recent data point towards the role of ganglioside epitopes by immunohistochemical methods. Ultimately, the syndrome results from a permissive genetic background on which environmental factors, including infections, vaccination and the influence of aging, lead to disease. © 2016 Informa UK Limited, trading as Taylor and Francis Group.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1080/1744666X.2016.1193006
dc.identifier.issn1744666X
dc.identifier.issn17448409
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/24042
dc.language.isoengspa
dc.publisherTaylor and Francis Ltdspa
dc.relation.citationEndPage1189
dc.relation.citationIssueNo. 11
dc.relation.citationStartPage1175
dc.relation.citationTitleExpert Review of Clinical Immunology
dc.relation.citationVolumeVol. 12
dc.relation.ispartofExpert Review of Clinical Immunology, ISSN:1744666X, 17448409, Vol.12, No.11 (2016); pp. 1175-1189spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84992052404&doi=10.1080%2f1744666X.2016.1193006&partnerID=40&md5=4592c2dd34d40a63fa444b668a01d3cfspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordEpitopespa
dc.subject.keywordGanglioside antibodyspa
dc.subject.keywordAutoantibodyspa
dc.subject.keywordGangliosidespa
dc.subject.keywordAgingspa
dc.subject.keywordAntibody blood levelspa
dc.subject.keywordCampylobacteriosisspa
dc.subject.keywordClinical featurespa
dc.subject.keywordDifferential diagnosisspa
dc.subject.keywordEnvironmental factorspa
dc.subject.keywordGuillain barre syndromespa
dc.subject.keywordHumanspa
dc.subject.keywordImmunohistochemistryspa
dc.subject.keywordImmunopathogenesisspa
dc.subject.keywordMacrophage activationspa
dc.subject.keywordNonhumanspa
dc.subject.keywordReviewspa
dc.subject.keywordT lymphocytespa
dc.subject.keywordCampylobacter jejunispa
dc.subject.keywordCampylobacteriosisspa
dc.subject.keywordCross reactionspa
dc.subject.keywordGenotype environment interactionspa
dc.subject.keywordGuillain barre syndromespa
dc.subject.keywordImmunologyspa
dc.subject.keywordImmunotherapyspa
dc.subject.keywordMetabolismspa
dc.subject.keywordProceduresspa
dc.subject.keywordAgingspa
dc.subject.keywordAutoantibodiesspa
dc.subject.keywordCampylobacter infectionsspa
dc.subject.keywordCampylobacter jejunispa
dc.subject.keywordCross reactionsspa
dc.subject.keywordGangliosidesspa
dc.subject.keywordGene-environment interactionspa
dc.subject.keywordGuillain-barre syndromespa
dc.subject.keywordHumansspa
dc.subject.keywordImmunotherapyspa
dc.subject.keywordAutoimmune neuropathyspa
dc.subject.keywordGuillain-barréspa
dc.subject.keywordImmune tolerancespa
dc.subject.keywordInfection and immunityspa
dc.subject.keywordMolecular mimicryspa
dc.titleGuillain-Barré syndrome: causes, immunopathogenic mechanisms and treatmentspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
Archivos
Colecciones
Artículos