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Risk Factors Associated with Different Stages of Atherosclerosis in Colombian Patients with Rheumatoid Arthritis

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dc.creatorRojas-Villarraga, Adrianaspa
dc.creatorOrtega-Hernandez, Oscar-Danilospa
dc.creatorGomez, Luis F.spa
dc.creatorPardo, Aryce L.spa
dc.creatorLópez Guzmán, Silvia
dc.creatorArango-Ferreira, Camilaspa
dc.creatorHincapie, Maria-Eugeniaspa
dc.creatorBetancur, Juan F.spa
dc.creatorPineda-Tamayo, Ricardospa
dc.creatorDiaz, Francisco J.spa
dc.creatorAnaya, Juan-Manuelspa
dc.date.accessioned2020-08-06T16:20:44Z
dc.date.available2020-08-06T16:20:44Z
dc.date.created2008-10-01spa
dc.description.abstractRheumatoid arthritis (RA) is associated with an increased prevalence of cardiovascular disease (CVD). Since atherosclerosis development is a gradual process of damage inside the artery wall, and the phenotype–genotype correlation of complex diseases may vary depending on ethnicity, we sought to investigate the influence of clinical features, routine inflammatory markers, and the genetic component of RA on different stages of atherosclerosis in northwestern Colombian patients with RA. Methods A group of 140 patients with RA were enrolled in this study. All patients underwent a noninvasive evaluation of endothelial function by flow-mediated vasodilation (FMV) and an assessment of carotid intima-media thickness (IMT) by high-resolution B-mode ultrasonography. The patients were classified into 3 categories: endothelial dysfunction (FMV <5%), increased IMT (0.91-1.29 mm), and plaque (IMT >1.30 mm). The risk of being in each category was assessed by investigating traditional and nontraditional cardiovascular risk factors. For each stage of atherosclerosis development, we searched for nontraditional risk factors that were significantly associated with the stage after adjusting for traditional risk factors and current age.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.semarthrit.2008.01.019
dc.identifier.issnISSN: 0049-0172
dc.identifier.issnEISSN: 1532-866X
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/26125
dc.language.isoengspa
dc.publisherElsevierspa
dc.relation.citationEndPage82
dc.relation.citationIssueNo. 2
dc.relation.citationStartPage71
dc.relation.citationTitleSeminars in Arthritis and Rheumatism
dc.relation.citationVolumeVol. 38
dc.relation.ispartofSeminars in Arthritis and Rheumatism, ISSN: 0049-0172 ; EISSN: 1532-866X, Vol.38, No.2 (October, 2008); pp.71-82spa
dc.relation.urihttps://www.sciencedirect.com/science/article/abs/pii/S0049017208000437?via%3Dihubspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.sourceSeminars in Arthritis and Rheumatismspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordAdultspa
dc.subject.keywordArthritisspa
dc.subject.keywordRheumatoidspa
dc.subject.keywordCarotid Artery Diseasesspa
dc.subject.keywordColombiaspa
dc.subject.keywordEndotheliumspa
dc.subject.keywordVascularspa
dc.subject.keywordFemalespa
dc.subject.keywordHumansspa
dc.subject.keywordMalespa
dc.subject.keywordMiddle Agedspa
dc.subject.keywordRheumatoid Factorspa
dc.subject.keywordRisk Assessmentspa
dc.subject.keywordRisk Factorsspa
dc.subject.keywordSeverity of Illness Indexspa
dc.subject.keywordTunica Intimaspa
dc.subject.keywordTunica Mediaspa
dc.subject.keywordUltrasonographyspa
dc.titleRisk Factors Associated with Different Stages of Atherosclerosis in Colombian Patients with Rheumatoid Arthritisspa
dc.title.TranslatedTitleFactores de riesgo asociados con diferentes etapas de la aterosclerosis en pacientes colombianos con artritis reumatoidespa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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