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Multiple facets in the control of acromegaly

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dc.creatorVilar, Luciospa
dc.creatorValenzuela, Alexspa
dc.creatorRibeiro-Oliveira, Antôniospa
dc.creatorGómez Giraldo, Claudia M.spa
dc.creatorPantoja, Dolyspa
dc.creatorBronstein, Marcello D.spa
dc.date.accessioned2020-08-06T16:20:33Z
dc.date.available2020-08-06T16:20:33Z
dc.date.created2014-01spa
dc.description.abstractAims The current article provides a brief overview of the criteria for defining disease control in acromegaly. Methods This was a retrospective, narrative review of previously published evidence chosen at the author’s discretion along with an illustrative case study from Latin America. Findings and Conclusions In the strictest sense, “cure” in acromegaly is defined as complete restoration of normal pulsatile growth hormone secretion, although this is rarely achieved. Rather than “cure”, as such, it is more appropriate to refer to disease control and remission, which is defined mainly in terms of specific biochemical targets (for growth hormone and insulin-like growth factor-1) that predict or correlate with symptoms, comorbidities and mortality. However, optimal management of acromegaly goes beyond biochemical control to include control of tumour growth (which may be independent of biochemical control) and comprehensive management of the symptoms and comorbidities typically associated with the disease, as these may not be adequately managed with acromegaly-specific therapy alone.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1007/s11102-013-0536-7
dc.identifier.issnISSN: 1573-7403
dc.identifier.issnEISSN: 1386-341X
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/26058
dc.language.isoengspa
dc.publisherSpringer Naturespa
dc.relation.citationEndPage17
dc.relation.citationIssueNo. Suppl 1
dc.relation.citationStartPage11
dc.relation.citationTitlePituitary
dc.relation.citationVolumeVol. 17
dc.relation.ispartofPituitary, ISSN: 1573-7403, 1386-341X, Vol.17, No.Suppl 1 (2014-01); pp.11-17spa
dc.relation.urihttps://link.springer.com/content/pdf/10.1007%2Fs11102-013-0536-7.pdfspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.sourcePituitaryspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordAcromegalyspa
dc.subject.keywordAdenomaspa
dc.subject.keywordAdultspa
dc.subject.keywordComorbidityspa
dc.subject.keywordDiabetes Mellitusspa
dc.subject.keywordDopamine Agonistsspa
dc.subject.keywordDyslipidemiasspa
dc.subject.keywordFemalespa
dc.subject.keywordGrowth Hormone-Secreting Pituitary Adenomaspa
dc.subject.keywordHuman Growth Hormonespa
dc.subject.keywordHumansspa
dc.subject.keywordHypertensionspa
dc.subject.keywordInsulin-Like Growth Factor Ispa
dc.subject.keywordRetrospective Studiesspa
dc.subject.keywordSomatostatinspa
dc.subject.keywordThyroid Neoplasmsspa
dc.subject.keywordTreatment Outcomespa
dc.titleMultiple facets in the control of acromegalyspa
dc.title.TranslatedTitleMúltiples facetas en el control de la acromegalia.spa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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