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Electrochemical and Optical Carbon Dots and Glassy Carbon Biosensors: A Review on Their Development and Applications in Early Cancer Detection

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dc.creatorFonthal, Farukspa
dc.creatorRodriguez Burbano, Diana Consuelospa
dc.creatorOndo Méndez, Alejandro Oyonospa
dc.creatorCalvo, Paulo C.spa
dc.creatorGarcía, Valentinaspa
dc.creatorArias, Valentinaspa
dc.creatorMuñoz, Marianaspa
dc.creatorLópez, Juana G.spa
dc.date.accessioned2025-07-21T16:41:02Z
dc.date.available2025-07-21T16:41:02Z
dc.date.created2025-02-01spa
dc.date.issued2025-02-01spa
dc.description.abstractCancer remains one of the leading causes of mortality worldwide, making early detection a critical factor in improving patient outcomes and survival rates. Developing advanced biosensors is essential for achieving early detection and accurate cancer diagnosis. This review offers a comprehensive overview of the development and application of carbon dots (CDs) and glassy carbon (GC) biosensors for early cancer detection. It covers the synthesis of CDs and GC, electrode fabrication methods, and electrochemical and optical transduction principles. This review explores various biosensors, including enzymatic and non-enzymatic, and discusses key biomarkers relevant to cancer detection. It also examines characterization techniques for electrochemical and optical biosensors, such as electrochemical impedance spectroscopy, cyclic voltammetry, UV–VIS, and confocal microscopy. The findings highlight the advancements in biosensor performance, emphasizing improvements in sensitivity, selectivity, and stability, as well as underscoring the potential of integrating different transduction methods and characterization approaches to enhance early cancer detection.eng
dc.format.mimetypeapplication/pdfspa
dc.identifier.doihttps://doi.org/10.3390/mi16020139spa
dc.identifier.issn2072-666Xspa
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/46058
dc.language.isoengspa
dc.publisherMDPIspa
dc.relation.ispartofMicromachines 2025, 16(2), 139spa
dc.relation.urihttps://www.mdpi.com/2072-666X/16/2/139spa
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccessspa
dc.rights.accesoAbierto (Texto Completo)spa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/spa
dc.sourceMicromachinesspa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordIngeniería mecánicaeng
dc.subject.keywordBiosensorseng
dc.subject.keywordCarbon dotseng
dc.subject.keywordCancereng
dc.subject.keywordElectrochemical biosensoreng
dc.subject.keywordGlassy carboneng
dc.subject.keywordOptical biosensoreng
dc.titleElectrochemical and Optical Carbon Dots and Glassy Carbon Biosensors: A Review on Their Development and Applications in Early Cancer Detectionspa
dc.typearticlespa
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersionspa
dc.type.spaArtículo de revisiónspa
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