Ítem
Solo Metadatos

Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO

Mostrar el registro sencillo de la publicación
dc.creatorCaicedo Dorado, Alexander
dc.creatorElwell, Clare Espa
dc.creatorHoskote, Aparnaspa
dc.creatorElliott, Martin Jspa
dc.creatorPapademetriou, Maria Dspa
dc.creatorVan Huffel, Sabinespa
dc.date.accessioned2020-08-28T15:49:59Z
dc.date.available2020-08-28T15:49:59Z
dc.date.created2012-07-21spa
dc.description.abstractNeonates supported on extracorporeal membrane oxygenation (ECMO) are at high risk of brain injury due to haemodynamic instability. In order to monitor cerebral and peripheral (muscle) haemodynamic and oxygenation changes in this population we used a dual-channel near-infrared spectroscopy (NIRS) system. In addition, to assess interrelations between NIRS and systemic variables, collected simultaneously, canonical correlation analysis (CCA) was employed. CCA can quantify the relationship between a set of variables and assess levels of dependency. In four out of five patients, systemic variables were found to be less inter-related with cerebral rather than peripheral NIRS measurements. Moreover, during ECMO flow manipulations, we found that the interrelation between the systemic and the NIRS cerebral/peripheral variables changed. The CCA method presented here can be used to assess differences between NIRS cerebral and NIRS peripheral responses due to systemic variations which may be indicative of physiological differences in the mechanisms that regulate oxygenation and/or haemodynamics of the brain and the muscle.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1007/978-1-4614-4989-8_4
dc.identifier.issnISBN: 978-1-4614-4771-9
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/28878
dc.language.isoengspa
dc.publisherSpringer Naturespa
dc.relation.citationEndPage29
dc.relation.citationStartPage23
dc.relation.citationTitleAdvances in Experimental Medicine and Biology
dc.relation.citationVolumeVol. 765
dc.relation.ispartofAdvances in Experimental Medicine and Biology, ISBN: 978-1-4614-4771-9, Vol.765 (2012); pp. 23-29spa
dc.relation.urihttps://link.springer.com/chapter/10.1007/978-1-4614-4989-8_4spa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourceAdvances in Experimental Medicine and Biologyspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordECMOspa
dc.titleCanonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMOspa
dc.title.TranslatedTitleAnálisis de correlación canónica en el estudio de las interrelaciones de la hemodinámica cerebral y periférica con variables sistémicas en recién nacidos admitidos en ECMOspa
dc.typebookParteng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaParte de librospa
Archivos
Colecciones
Libros y capítulos de libro