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Cardiac impact of hypoglycaemia

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dc.creatorde León Espitia, Marco Antoniospa
dc.date.accessioned2020-05-25T23:59:10Z
dc.date.available2020-05-25T23:59:10Z
dc.date.created2017spa
dc.description.abstractAcute or chronic hypoglycaemia, induced by insulin or other oral antidiabetic drugs in a therapeutic context, constitutes a cardiovascular risk factor. It leads to endothelial dysfunction and atherogenesis through pro-inflammatory mechanisms, as much as or more important than hyperglycaemia, with the aggravating factor of inducing arrhythmogenic and ischaemic sudden death. Conclusion Hypoglycaemia is a real threat for the myocardium, not only due to its immediate pro-arrhythmic effects, that may be associated with sudden death syndrome, but also due to the pro-inflammatory and atherogenic effects. These are all significant risk factors for the development of cardiovascular disease, making it desirable, and clinically relevant to prevent hypoglycaemic episodes of any intensity and duration in any type of diabetic patient. This is particularly important in those that have a pathological myocardial substrate that can lead to an increase in the risk of sudden death: compromised systole function, ventricular arrhythmias, atrial fibrillation, coronary disease, hypertrophic cardiomyopathy, arrhythmogenic genotype, and a history of resuscitation. © 2017 Sociedad Colombiana de Cardiología y Cirugía Cardiovasculareng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.rccar.2016.12.002
dc.identifier.issn1205633
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/22997
dc.language.isoengspa
dc.publisherElsevier B.V.spa
dc.relation.citationEndPage381
dc.relation.citationIssueNo. 4
dc.relation.citationStartPage376
dc.relation.citationTitleRevista Colombiana de Cardiologia
dc.relation.citationVolumeVol. 24
dc.relation.ispartofRevista Colombiana de Cardiologia, ISSN:1205633, Vol.24, No.4 (2017); pp. 376-381spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85019463818&doi=10.1016%2fj.rccar.2016.12.002&partnerID=40&md5=2000ba19e11420c819402e86547a924espa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordInsulinspa
dc.subject.keywordArrhythmogenesisspa
dc.subject.keywordAtherogenesisspa
dc.subject.keywordAtrial fibrillationspa
dc.subject.keywordCardiac musclespa
dc.subject.keywordCardiovascular diseasespa
dc.subject.keywordCardiovascular effectspa
dc.subject.keywordCardiovascular riskspa
dc.subject.keywordCoronary artery diseasespa
dc.subject.keywordDiabetes mellitusspa
dc.subject.keywordDiabetic patientspa
dc.subject.keywordDisease durationspa
dc.subject.keywordEndothelial dysfunctionspa
dc.subject.keywordHeart ventricle arrhythmiaspa
dc.subject.keywordHumanspa
dc.subject.keywordHypertrophic cardiomyopathyspa
dc.subject.keywordHypoglycemiaspa
dc.subject.keywordLife threatspa
dc.subject.keywordResuscitationspa
dc.subject.keywordShort surveyspa
dc.subject.keywordSudden cardiac deathspa
dc.subject.keywordSystolic dysfunctionspa
dc.subject.keywordArrhythmiasspa
dc.subject.keywordGlucosespa
dc.subject.keywordMyocardiumspa
dc.subject.keywordVascularspa
dc.titleCardiac impact of hypoglycaemiaspa
dc.title.TranslatedTitleImpacto cardiovascular de la hipoglicemiaspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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