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Can physical activity attenuate the negative association between sitting time and cognitive function among older adults? A mediation analysis

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dc.creatorGarcía-Hermoso, Antoniospa
dc.creatorRamírez-Vélez, Robinsonspa
dc.creatorCelis-Morales, Carlos A.spa
dc.creatorOlloquequi, Jordispa
dc.creatorIzquierdo, Mikelspa
dc.date.accessioned2020-05-26T00:07:49Z
dc.date.available2020-05-26T00:07:49Z
dc.date.created2018spa
dc.description.abstractThe purpose of this study was to examine the combined association of sitting time and physical activity with cognitive function and to determine whether moderate-to-vigorous physical activity (MVPA) is a mediator of the association between sitting time and cognitive function in a nationally representative sample of older adults from Chile. Data from 989 older adults (?65 years old, 61.3% female) from the 2009–2010 Chilean Health Survey were analyzed. Physical activity and sitting time were measured using the Global Physical Activity questionnaire. Cognitive function was assessed using the modified Mini-Mental State levels Examination. Physical activity levels were categorized as “inactive” ( less than 600 metabolic equivalent value minutes per week) or “active” (?600 metabolic equivalent value minutes per week). Sitting time was categorized as “sedentary”, defined as ?4 h of reported sitting time per day, or “non-sedentary”, defined as less than 4 h. We created the following groups (i) non-sedentary/active; (ii) non-sedentary/inactive; (iii) sedentary/active; and (iv) sedentary/inactive. Hayes's PROCESS macro was used for the simple mediation analysis. Compared with the reference group (individuals classified as non-sedentary/active), older adults who were classified as sedentary/active had elevated odds of cognitive impairment (OR = 1.90, [95% CI, 1.84 to 3.85]). However, the odds ratio for cognitive impairment was substantially increased in those classified as sedentary/inactive (OR = 4.85 [95% CI, 2.54 to 6.24]) compared with the reference group. MVPA was found to mediate the relationship between sitting time and cognitive function (Indirect Effect = ?0.070 [95% CI, ?0.012 to ?0.004]). Conclusion: The present findings suggest that, whether overall physical activity is high or low, spending large amounts of time sitting is associated with elevated odds of cognitive impairment and that MVPA slightly weakens the relationship between sitting time and cognitive function. © 2018 Elsevier Inc.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.exger.2018.03.002
dc.identifier.issn5315565
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/24034
dc.language.isoengspa
dc.publisherElsevier Inc.spa
dc.relation.citationEndPage177
dc.relation.citationStartPage173
dc.relation.citationTitleExperimental Gerontology
dc.relation.citationVolumeVol. 106
dc.relation.ispartofExperimental Gerontology, ISSN:5315565, Vol.106,(2018); pp. 173-177spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85043999950&doi=10.1016%2fj.exger.2018.03.002&partnerID=40&md5=df7e049e9c2ba61b299077463fddebd3spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAgedspa
dc.subject.keywordAlcohol consumptionspa
dc.subject.keywordArticlespa
dc.subject.keywordAttentionspa
dc.subject.keywordBody massspa
dc.subject.keywordCognitive defectspa
dc.subject.keywordComposite international diagnostic interviewspa
dc.subject.keywordControlled studyspa
dc.subject.keywordDepressionspa
dc.subject.keywordDepression assessmentspa
dc.subject.keywordDisease associationspa
dc.subject.keywordDsm-ivspa
dc.subject.keywordFemalespa
dc.subject.keywordHumanspa
dc.subject.keywordLanguagespa
dc.subject.keywordMajor clinical studyspa
dc.subject.keywordMalespa
dc.subject.keywordMemoryspa
dc.subject.keywordMetabolic equivalentspa
dc.subject.keywordMini mental state examinationspa
dc.subject.keywordOrientationspa
dc.subject.keywordPhysical activityspa
dc.subject.keywordPrevalencespa
dc.subject.keywordPriority journalspa
dc.subject.keywordSittingspa
dc.subject.keywordTobacco usespa
dc.subject.keywordAgingspa
dc.subject.keywordChilespa
dc.subject.keywordCognitionspa
dc.subject.keywordCognitive defectspa
dc.subject.keywordCross-sectional studyspa
dc.subject.keywordExercisespa
dc.subject.keywordHealth surveyspa
dc.subject.keywordPsychological rating scalespa
dc.subject.keywordPsychologyspa
dc.subject.keywordStatistical modelspa
dc.subject.keywordVery elderlyspa
dc.subject.keywordAgedspa
dc.subject.keywordAged, 80 and overspa
dc.subject.keywordAgingspa
dc.subject.keywordChilespa
dc.subject.keywordCognitionspa
dc.subject.keywordCognitive dysfunctionspa
dc.subject.keywordCross-sectional studiesspa
dc.subject.keywordExercisespa
dc.subject.keywordFemalespa
dc.subject.keywordHealth surveysspa
dc.subject.keywordHumansspa
dc.subject.keywordLogistic modelsspa
dc.subject.keywordMalespa
dc.subject.keywordPsychiatric status rating scalesspa
dc.subject.keywordSedentary behaviorspa
dc.subject.keywordAgingspa
dc.subject.keywordCognitive impairmentspa
dc.subject.keywordPhysical inactivityspa
dc.subject.keywordSedentary behaviorspa
dc.titleCan physical activity attenuate the negative association between sitting time and cognitive function among older adults? A mediation analysisspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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