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Host and Toxoplasma gondii genetic and non-genetic factors influencing the development of ocular toxoplasmosis: A systematic review

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dc.creatorFernández C.spa
dc.creatorJaimes J.spa
dc.creatorOrtiz M.C.spa
dc.creatorRamírez, Juan Davidspa
dc.date.accessioned2020-05-26T00:11:24Z
dc.date.available2020-05-26T00:11:24Z
dc.date.created2016spa
dc.description.abstractToxoplasmosis is a cosmopolitan infection caused by the apicomplexan parasite Toxoplasma gondii. This infectious disease is widely distributed across the world where cats play an important role in its spread. The symptomatology caused by this parasite is diverse but the ocular affectation emerges as the most important clinical phenotype. Therefore, we conducted a systematic review of the current knowledge of ocular toxoplasmosis from the genetic diversity of the pathogen towards the treatment available for this infection. This review represents an update to the scientific community regarding the genetic diversity of the parasite, the genetic factors of the host, the molecular pathogenesis and its association with disease, the available diagnostic tools and the available treatment of patients undergoing ocular toxoplamosis. This review will be an update for the scientific community in order to encourage researchers to deploy cutting-edge investigation across this field. © 2016 Elsevier B.V.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.meegid.2016.06.053
dc.identifier.issn15671348
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/24300
dc.language.isoengspa
dc.publisherElsevier B.V.spa
dc.relation.citationEndPage209
dc.relation.citationStartPage199
dc.relation.citationTitleInfection, Genetics and Evolution
dc.relation.citationVolumeVol. 44
dc.relation.ispartofInfection, Genetics and Evolution, ISSN:15671348, Vol.44,(2016); pp. 199-209spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84978204119&doi=10.1016%2fj.meegid.2016.06.053&partnerID=40&md5=189f0f03aa2d68144e68057093c0b897spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAtovaquonespa
dc.subject.keywordoculareng
dc.subject.keywordAzithromycinspa
dc.subject.keywordcellulareng
dc.subject.keywordhumoraleng
dc.subject.keywordClarithromycinspa
dc.subject.keywordClindamycinspa
dc.subject.keywordCotrimoxazolespa
dc.subject.keywordCytokinespa
dc.subject.keywordDexamethasonespa
dc.subject.keywordDoxycyclinespa
dc.subject.keywordGatifloxacinspa
dc.subject.keywordHost factorspa
dc.subject.keywordInflammasomespa
dc.subject.keywordLipid metabolism proteinspa
dc.subject.keywordPrednisolonespa
dc.subject.keywordProtein micspa
dc.subject.keywordProtein ropspa
dc.subject.keywordPyrimethaminespa
dc.subject.keywordSpiramycinspa
dc.subject.keywordToll like receptorspa
dc.subject.keywordTrovafloxacinspa
dc.subject.keywordUnclassified drugspa
dc.subject.keywordAntiparasitic agentspa
dc.subject.keywordCell adhesionspa
dc.subject.keywordCellular immunityspa
dc.subject.keywordDrug mechanismspa
dc.subject.keywordGenetic predispositionspa
dc.subject.keywordGenetic variabilityspa
dc.subject.keywordHeredityspa
dc.subject.keywordHost cellspa
dc.subject.keywordHumanspa
dc.subject.keywordHumoral immunityspa
dc.subject.keywordLipid metabolismspa
dc.subject.keywordNonhumanspa
dc.subject.keywordOncogene c mycspa
dc.subject.keywordPathogenesisspa
dc.subject.keywordPathophysiologyspa
dc.subject.keywordPhenotypespa
dc.subject.keywordPriority journalspa
dc.subject.keywordReviewspa
dc.subject.keywordSymptomspa
dc.subject.keywordSystematic reviewspa
dc.subject.keywordToxoplasma gondiispa
dc.subject.keywordToxoplasmosisspa
dc.subject.keywordAnimalspa
dc.subject.keywordGeneticsspa
dc.subject.keywordHost parasite interactionspa
dc.subject.keywordImmunologyspa
dc.subject.keywordOcular toxoplasmosisspa
dc.subject.keywordParasitologyspa
dc.subject.keywordToxoplasmaspa
dc.subject.keywordAnimalsspa
dc.subject.keywordAntiparasitic agentsspa
dc.subject.keywordGenetic predisposition to diseasespa
dc.subject.keywordHost-parasite interactionsspa
dc.subject.keywordHumansspa
dc.subject.keywordImmunityeng
dc.subject.keywordImmunityeng
dc.subject.keywordToxoplasmaspa
dc.subject.keywordToxoplasmosiseng
dc.subject.keywordEyespa
dc.subject.keywordInfectious diseasesspa
dc.subject.keywordToxoplasma gondiispa
dc.subject.keywordToxoplasmosisspa
dc.titleHost and Toxoplasma gondii genetic and non-genetic factors influencing the development of ocular toxoplasmosis: A systematic reviewspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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