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PROTECTIVE ROLE OF ACTIVATED PROTEIN C AGAINST APOPTOSIS IN NEURONAL AND ENDOTHELIAL MODELS

dc.creatorMorales, L.C.spa
dc.creatorDíaz, J.spa
dc.creatorCamargo, M.H.spa
dc.creatorArboleda, H.spa
dc.creatorArboleda, G.spa
dc.creatorMatheus Merino, Luisa Marinaspa
dc.date.accessioned2020-08-28T15:48:15Z
dc.date.available2020-08-28T15:48:15Z
dc.date.created2009-02-01spa
dc.description.abstractThe neurodegenerative diseases are the result of the interaction of several factors that converge in neuronal death. Neuronalapoptosis is believe to have a mayor physiophatological role in this process which is accompanied by alterations in thevascular brain endothelium, contributing to alterations in the blood-brain barrier, a key regulator of neuronal survival/death equilibrium. Increased levels of the sphingolipid ceramide have been described in diverse neurodegenerative disorders and following several cellular stress insults and is believe to contribute to thepathophysiology of neuronal death.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1111/j.1471-4159.2009.05818.x
dc.identifier.issnISSN: 1471-4159
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/28463
dc.language.isoengspa
dc.publisherJohn Wiley & Sonsspa
dc.relation.citationEndPage86
dc.relation.citationIssueNo. 1
dc.relation.citationStartPage85
dc.relation.citationTitleJournal of Neurochemistry
dc.relation.citationVolumeVol. 108
dc.relation.ispartofJournal of Neurochemistry, ISSN:1471-4159, Vol. 108, Issues 1 Special Issue: Abstracts of the American Society for Neurochemistry 40th Annual Meeting 7–11 March Charleston SC USA (February, 2009); pp. 85-86spa
dc.relation.urihttps://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1471-4159.2009.05818.xspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.sourceJournal of Neurochemistryspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordNeurodegenerative diseasesspa
dc.subject.keywordNeuronalapoptosisspa
dc.subject.keywordAlterations in thevascular brain endotheliumspa
dc.subject.keywordKey regulator of neuronal survival/death equilibriumspa
dc.subject.keywordPathophysiology of neuronal deathspa
dc.titlePROTECTIVE ROLE OF ACTIVATED PROTEIN C AGAINST APOPTOSIS IN NEURONAL AND ENDOTHELIAL MODELSspa
dc.title.TranslatedTitlePAPEL PROTECTOR DE LA PROTEÍNA C ACTIVADA CONTRA LA APOPTOSIS EN MODELOS NEURONALES Y ENDOTELIALESspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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