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Nodular Necrotizing-Scleritis Associated with Epstein-Barr Virus Infection: A Case Report
| dc.creator | Bustos-Mejia D.A. | spa |
| dc.creator | Parra-Medina R. | spa |
| dc.creator | de-la-Torre, Alejandra | spa |
| dc.date.accessioned | 2020-05-25T23:57:38Z | |
| dc.date.available | 2020-05-25T23:57:38Z | |
| dc.date.created | 2019 | spa |
| dc.description.abstract | Purpose: To report a case of necrotizing scleritis associated with Epstein-Barr virus (EBV) infection. Case report: A 68-year-old woman with a history of scleral ulcer, perforation, and scleral graft, with initial negative studies for infectious processes and autoimmune systemic-diseases consulted our service for a second opinion after 2 years of treatment without improvement. She presented severe conjunctival and scleral hyperemia, vascular tortuosity in 360°, areas of scleral thinning and an elevated lesion of nodular appearance. EBV serologic antibody IgG titers were strongly positive and IgM titers were borderline. A scleral biopsy showed granulation tissue with severe inflammation without the presence of tumor cells; PCR was positive for EBV. The patient was treated with antiviral therapy with resolution of the scleritis. Conclusions: EBV although rare, should be considered as a differential diagnosis in patients with necrotizing scleritis with no improvement to conventional therapy. © 2019, © 2019 Taylor and Francis Group, LLC. | eng |
| dc.format.mimetype | application/pdf | |
| dc.identifier.doi | https://doi.org/10.1080/09273948.2019.1611877 | |
| dc.identifier.issn | 9273948 | |
| dc.identifier.uri | https://repository.urosario.edu.co/handle/10336/22710 | |
| dc.language.iso | eng | spa |
| dc.publisher | Taylor and Francis Ltd | spa |
| dc.relation.citationTitle | Ocular Immunology and Inflammation | |
| dc.relation.ispartof | Ocular Immunology and Inflammation, ISSN:9273948,(2019) | spa |
| dc.relation.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85073987893&doi=10.1080%2f09273948.2019.1611877&partnerID=40&md5=01ead083cfe084761722e578cd45ae1f | spa |
| dc.rights.accesRights | info:eu-repo/semantics/openAccess | |
| dc.rights.acceso | Abierto (Texto Completo) | spa |
| dc.source.instname | instname:Universidad del Rosario | spa |
| dc.source.reponame | reponame:Repositorio Institucional EdocUR | spa |
| dc.subject.keyword | Epstein-Barr virus (EBV) | spa |
| dc.subject.keyword | Necrotizing scleritis | spa |
| dc.subject.keyword | PCR | spa |
| dc.title | Nodular Necrotizing-Scleritis Associated with Epstein-Barr Virus Infection: A Case Report | spa |
| dc.type | other | eng |
| dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | |
| dc.type.spa | Artículo | spa |
