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Evidence and Consensus-Based Imaging Guidelines in Multifocal Choroiditis With Panuveitis and Punctate Inner Choroiditis—Multimodal Imaging in Uveitis (MUV) Taskforce Report 5

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dc.creatorGupta, Vishalispa
dc.creatorSarraf, Davidspa
dc.creatorJabs, Douglas A.spa
dc.creatorFawzi, Amanispa
dc.creatorAccorinti, Massimospa
dc.creatorShantha, Jessica G.spa
dc.creatorAgrawal, Rupeshspa
dc.creatorInvernizzi, Alessandrospa
dc.creatorSadda, Srinivasspa
dc.creatorBiswas, Jyotirmayspa
dc.creatorAltaweel, Michaelspa
dc.creatorde la Torre Cifuentes, Ligia Alejandraspa
dc.creatorThorne, Jennifer E.spa
dc.creatorTsui, Edmundspa
dc.creatorOssewaarde-van Norel, Jeannettespa
dc.creatorAgarwal, Aniruddhaspa
dc.creatorGangaputra, Sapnaspa
dc.date.accessioned2025-07-21T16:41:29Z
dc.date.available2025-07-21T16:41:29Z
dc.date.created2025-08-01spa
dc.date.issued2025-08-01spa
dc.description.abstractPURPOSE: To develop imaging and consensus-based guidelines on the application of multimodal imaging in noninfectious multifocal choroiditis and panuveitis (MFCPU) and punctate inner choroiditis (PIC). DESIGN: Consensus agreement guided by the review of literature and an expert committee using nominal group technique (NGT). METHODS: An expert committee applied a timed structured nominal group technique (NGT) to achieve consensus-based recommendations on specific disease characteristics, biomarkers of activity, and complications for MFCPU and PIC. Representative cases with noninfectious active and inactive MFCPU and PIC with color fundus photographs (CFP), optical coherence tomography (OCT), fundus fluorescein angiography (FFA), OCT angiography (OCTA), indocyanine angiography (ICGA), and fundus autofluorescence images (FAF) were reviewed. These recommendations were voted upon by the entire task force. RESULTS: The experts agreed that lesions of MFCPU and PIC can be well characterized using CFP. OCT is the preferred modality for detecting active lesions. Both FAF and OCT are effective for monitoring disease recurrence. Late-phase ICGA is most valuable in recurrent disease when the lesions are not visible on FAF and CFP. While OCTA and ICGA can successfully identify lesions and complications such as choroidal neovascularization, no imaging biomarkers were found to reliably distinguish between active and inactive lesions on these two modalities. CONCLUSIONS: Incorporating imaging findings, particularly OCT, into the Standardization of Uveitis Nomenclature (SUN) classification criteria for MFCPU and PIC enables more precise assessment of disease activity. These consensus-based guidelines provide a framework for selecting optimal imaging modalities for diagnosis, monitoring and identification of complications of MFCPU and PIC.eng
dc.format.mimetypeapplication/pdfspa
dc.identifier.doihttps://doi.org/10.1016/j.ajo.2025.04.018spa
dc.identifier.issn0002-9394spa
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/46059
dc.language.isoengspa
dc.publisherElsevierspa
dc.relation.ispartofAm J Ophthalmol 2025;276: 272– 285spa
dc.relation.urihttps://www.ajo.com/article/S0002-9394(25)00195-3/fulltextspa
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccessspa
dc.rights.accesoAbierto (Texto Completo)spa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/spa
dc.sourceAm J Ophthalmolspa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordMultimodal imagingeng
dc.subject.keywordNoninfectious multifocal choroiditis and panuveitis (MFCPU)eng
dc.subject.keywordPunctate inner choroiditis (PIC)eng
dc.subject.keywordConsensus-based guidelineseng
dc.titleEvidence and Consensus-Based Imaging Guidelines in Multifocal Choroiditis With Panuveitis and Punctate Inner Choroiditis—Multimodal Imaging in Uveitis (MUV) Taskforce Report 5spa
dc.typearticlespa
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersionspa
dc.type.spaArtículo de Investigaciónspa
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