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Efectividad de la vacuna Acelular Antipertusis en el embarazo y su protección al recién nacido : revisión sistemática

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dc.contributor.advisorÁlvarez, Martha Isabel
dc.contributor.advisorVillaveces, Mariana
dc.creatorRodriguez Basto, Lucia Marcela
dc.creator.degreeEspecialista en Pediatría
dc.date.accessioned2017-12-07T17:42:36Z
dc.date.available2017-12-07T17:42:36Z
dc.date.created2017-11-24
dc.date.issued2017
dc.descriptionSe trata de un revisión sistemática de la literatura para evaluar la evidencia sobre la efectividad de la vacuna acelular antipertussis mediante la medición de los niveles de anticuerpos contra B. pertussis en el neonato e infante menor de dos meses, reflejando el paso transplacentario de anticuerpos maternos contra la tosferina.spa
dc.description.abstractBackround: With the worldwide resurgence of pertusiss in 2011, and letal infection in neonates and infants under two months of age, new vaccination strategies have been sought to reduce infant mortality and prevent fatal cases of Bordetella pertussis, including vaccination of pregnant women, based on the effective passage of maternal antibodies to the neonate. Methods: Systematic review of articles literature to evaluate the effectiveness of vertical transference of antibodies to neonates with the application of the acellular antipertussis vaccine to provide protection to the newborn and the infant under 2 months – old. Results: After a rigorous search, 18 articles were included for analysis and extraction of evidence. The effectiveness of the Tdap vaccine exceeded 90% in neonates, taking into account the levels of antibodies in the same. The reactogenicity, in generall was low. Discussion: The vaccine against pertussis in pregnant women appears to be a safe, effective and accepted strategy to protect the newborn during the first weeks of life. For this reason it has been recommended for all pregnant women dduring each pregnancy, a measure adopted in different countries of Europe and in America including our country. Conclusion: Available evidence suggests that the Tdap vaccine may be recommended in pregnant women between week 27-36 of gestation, a period in which there is a greater transplacental passage of antibodies against pertussis. Accelerating Tdap in pregnant women is an effective strategy with no side effects and low cost. . Key words: Effectiveness, passive immunization, anti-pertussis acellular vaccines, newborn. eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.48713/10336_14136
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/14136
dc.language.isospa
dc.publisherUniversidad del Rosariospa
dc.publisher.departmentFacultad de medicinaspa
dc.publisher.programEspecialización en Pediatríaspa
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dc.rights.accesoAbierto (Texto Completo)spa
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dc.source.bibliographicCitationZhang L, Prietsch SO, Axelsson I, Halperin S a. Acellular vaccines for preventing whooping cough in children. Cochrane Database Syst Rev. 2011;(1):CD001478.
dc.source.bibliographicCitationWorld Health Organization. Laboratory manual for the diagnosis of whooping cough caused by Bordetella pertussis/ Bordetella parapertussis. 2007;04/14.
dc.source.bibliographicCitationVacunación de las embarazadas frente a la tos ferina en la comunidad de Valencia. De, Dirección General de Salud Pública Servicio de Salud Infantil y de la Mujer Servicio , Vigilancia y Control Epidemiológico. 2012;24.
dc.source.bibliographicCitationBlack RE S Cousens, H L Johnson, J E Lawn, I Rudan, D G Bassani, P Jha, H Campbell, C F Walker, R Cibulskis, T Eisele, L Liu CM. Global, regional, and national causes of child mortality in 2008: a systematic analysis. Child Health Epidemiology Reference Group of WHO and UNICEF. Lancet. 2010;375(9730):1969–1987.
dc.source.bibliographicCitationWorld Health Organization. WH. Weekly epidemiological record. No. 40. 2010;385–400. Available from: http://www.who.int/wer
dc.source.bibliographicCitationAl G et. Lineamiento Estratégico para la Introducción de la Vacuna TdaP (Tétanos - Difteria - Tos ferina acelular) en el Esquema del Programa Ampliado de Inmunizaciones –PAI Para Mujeres Gestantes de las cohortes 2013 y 2014. Colombia; 2013.
dc.source.bibliographicCitationFeigin RD, Cherry JD eds. Pertussis. Textbook of Pediatric Infectious Diseases 5th ed. 2003.
dc.source.bibliographicCitationHeininger U, Klich K SK and CJ. Clinical Findings in Bordetella pertussis Infections: Results of a Prospective Multicenter Surveillance Study. Pediatrics. 1997;100(6):E10.
dc.source.bibliographicCitationM. Riffelmann, C. H W Von König, V. Caro NG. Nucleic Acid amplification tests for diagnosis of Bordetella infections. J Clin Microbiol. 2005;43(10):4925–9.
dc.source.bibliographicCitationAbu Raya B, Srugo I, Kessel A, Peterman M, Vaknin A, Bamberger E. The Decline of Pertussis-Specific Antibodies After Tetanus, Diphtheria, and Acellular Pertussis Immunization in Late Pregnancy. J Infect Dis. 2015;212:1869–73.
dc.source.bibliographicCitationSukumaran L, McCarthy NL, Kharbanda EO, Weintraub ES, Vazquez-Benitez G, McNeil MM, et al. Safety of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis and Influenza Vaccinations in Pregnancy (ABSTRACT ONLY). Obstet Gynecol. 2015;(C):1.
dc.source.bibliographicCitationShakib JH, Korgenski K, Sheng X, Varner MW, Pavia AT, Byington CL. Tetanus, diphtheria, acellular pertussis vaccine during pregnancy: pregnancy and infant health outcomes. J Pediatr. 2013;163(5):1422-6-4.
dc.source.bibliographicCitationHealy CM, Rench MA, Baker CJ. Importance of timing of maternal combined tetanus, diphtheria, and acellular pertussis (Tdap) immunization and protection of young infants. Clin Infect Dis. 2013;56(4):539–44.
dc.source.bibliographicCitationTerranella A, Beeler Asay GB, Messonier ML, Clark TA, Liang JL. Pregnancy dose Tdap and postpartum cocooning to prevent infant pertussis: A decision analysis. Pediatrics. 2013;131(6):e1748–56.
dc.source.bibliographicCitationFulton TR, Phadke VK, Orenstein WA, Hinman AR, Johnson WD, Omer SB. Protective Effect of Contemporary Pertussis Vaccines: A Systematic Review and Meta-analysis. Clin Infect Dis. 2016;62:ciw051.
dc.source.bibliographicCitationRaya BA, Bamberger E, Almog M, Peri R, Srugo I, Kessel A. Immunization of pregnant women against pertussis: The effect of timing on antibody avidity. Vaccine. Elsevier Ltd; 2014;33(16):1948–52.
dc.source.bibliographicCitationVilajeliu A, Gonc A, Lopez M, Costa J, Rocamora L, R??os J, et al. Combined tetanus-diphtheria and pertussis vaccine during pregnancy: Transfer of maternal pertussis antibodies to the newborn. Vaccine. Elsevier Ltd; 2015;33(8):1056–62.
dc.source.bibliographicCitationGall SA, Myers J, Pichichero M. Maternal immunization with tetanusdiphtheriapertussis vaccine: Effect on maternal and neonatal serum antibody levels. Am J Obstet Gynecol. Elsevier Inc.; 2011;204(4):334.e1-334.e5.
dc.source.bibliographicCitationAlba Vilajeliu, Laia Ferrer, Jordina Munrós, Anna Goncé, Marta López, Josep Costa Bayas JM. Pertussis vaccination during pregnancy: Antibody persistence in infants. Vaccine. 2016.
dc.source.bibliographicCitationKirsten Maertensa, Raïssa Nadège Caboré, Kris Huygenb, Niel Hensc, Pierre Van Dammea EL. Pertussis vaccination during pregnancy in Belgium: Results of aprospective controlled cohort study. Vaccine. 2016
dc.source.bibliographicCitationTu Hoang H , Leuridan E, Maertens K , Dac Nguyen T, Hens N, Ha Vu N, Nadège Caboré R, Duong H, Huygen K , Van Damme P DA. Pertussis vaccination during pregnancy in Vietnam: Results of a randomized controlled trial Pertussis vaccination during pregnancy. Vaccine. 2015;
dc.source.bibliographicCitationEberhardt CS, Blanchard-Rohner G, Lemaître B, Boukrid M, Combescure C, Othenin-Girard V, et al. Maternal Immunization Earlier in Pregnancy Maximizes Antibody Transfer and Expected Infant Seropositivity Against Pertussis. Clin Infect Dis. 2016;ciw027
dc.source.bibliographicCitationMunoz FM, Bond NH, Maccato M, Pinell P, Hammill HA, Swamy GK, et al. Safety and Immunogenicity of Tetanus Diphtheria and Acellular Pertussis (Tdap) Immunization During Pregnancy in Mothers and Infants. Jama. 2014;311(17):1760.
dc.source.bibliographicCitationLeuridan E, Hens N, Peeters N, de Witte L, Van der Meeren O VDP. Effect of a prepregnancy pertussis booster dose on maternal antibody titers in young infants. Pediatr Infect Dis J. 2011;
dc.source.bibliographicCitationHardy-Fairbanks AJ, Pan SJ, Decker MD, Johnson DR, Greenberg DP KK, Talbot EA BH. Immune responses in infants whose mothers received Tdap vaccine during pregnancy. Pediatr Infect Dis J. 2013;
dc.source.bibliographicCitationErcan T, Sonmez C, Vural M, Erginoz E, Toruno glu M PY. Seroprevalance of pertussis antibodies in maternal and cord blood ofpreterm and termInfants. Vaccine. 2013
dc.source.bibliographicCitationDabrera G, Amirthalingam G, Andrews N, Campbell H, Ribeiro S, Kara E, et al. A case-control study to estimate the effectiveness of maternal pertussis vaccination in protecting newborn infants in England and Wales, 2012-2013. Clin Infect Dis. 2015;60(3):333–7.
dc.source.bibliographicCitationAmirthalingam G, Andrews N, Campbell H, Ribeiro S, Kara E, Donegan K, et al. Effectiveness of maternal pertussis vaccination in England: An observational study. Lancet. Elsevier Ltd; 2014;384(9953):1521–8.
dc.source.bibliographicCitationSukumaran L, McCarthy NL, Kharbanda EO, McNeil MM, Naleway AL, Klein NP, et al. Association of Tdap Vaccination With Acute Events and Adverse Birth Outcomes Among Pregnant Women With Prior Tetanus-Containing Immunizations. Jama. 2015;314(15):1581–7.
dc.source.bibliographicCitationMMWR. Updated recommendations for use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine (Tdap) in pregnant women and persons who have or anticipate having close contact with an infant aged <12 months – Advisory Committee on Immuniza. MMWR Morb Mortal Wkly Rep. 2011;60(41):1424.
dc.source.bibliographicCitationWorld Health Organization.. Pertussis vaccines: WHO position paper-August 2015. Weekly Epidemiological Record. World Heal Organ Geneva. 2015;90:433–60.
dc.source.bibliographicCitationAlba Vilajeliu ALG-B& JMB. Protecting newborns against pertussis: the value of vaccinating during pregnancy. Expert Rev Vaccines. 2015;14(8):1051–3.
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectEfectividadspa
dc.subjectInmunización pasivaspa
dc.subjectVacuna acelular antipertusisspa
dc.subjectRecién nacidospa
dc.subject.decsVacunas contra Difteria, Tétanos y Tos Ferina Acelular Quitarspa
dc.subject.decsAnticuerposspa
dc.subject.decsRecién Nacidospa
dc.subject.keywordEffectivenesseng
dc.subject.keywordPassive immunizationeng
dc.subject.keywordAnti-pertussiseng
dc.subject.keywordAcellular vaccineseng
dc.subject.keywordNewborneng
dc.titleEfectividad de la vacuna Acelular Antipertusis en el embarazo y su protección al recién nacido : revisión sistemáticaspa
dc.typemasterThesiseng
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaTrabajo de gradospa
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