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Differences in the cerebral hemodynamics regulation mechanisms of premature infants with intra-ventricular hemorrhage assessed by means of phase rectified signal averaging

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dc.creatorCaicedo Dorado, Alexander
dc.creatorNaulaers, Gspa
dc.creatorVan Huffelspa
dc.creatorVan Bel, Frankspa
dc.creatorLemmers, Petraspa
dc.creatorAlderliesten, Thomasspa
dc.creatorVaron, Carolinaspa
dc.date.accessioned2020-08-28T15:48:10Z
dc.date.available2020-08-28T15:48:10Z
dc.date.created2014-08-26spa
dc.description.abstractCerebral hemodynamics regulation consists of several mechanisms that try to keep brain homeostasis. In premature infants, due to the immaturity of their cerebral vascular bed, these mechanisms might be impaired exposing their brain to damage. The status of the cerebral regulation mechanism is classically assessed by measuring the coupling between some systemic variables, such as Mean arterial blood pressure (MABP) and concentration of blood gases, with surrogate measurements for cerebral blood flow, such as brain tissue oxygenation (rScO 2 ) measured by means of Near-infrared Spectroscopy. We hypothesized that the coupled dynamics between systemic variables and rScO 2 is different in premature infants that suffered from brain damage than in those with a favorable clinical outcome. Therefore, we explore the use of phase rectified signal averaging (PRSA) and bi-variate PRSA (BPRSA) in order to identify these differences. We found that the coupled dynamics between changes in MABP and cerebral oxygenation was different in premature infants that suffered III-IV grade intra-ventricular haemorrhage (IVH), when compared to control subjects.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps//doi.org 10.1109/EMBC.2014.6944552
dc.identifier.issnISSN: 1558-4615
dc.identifier.issnEISSN: 1094-687X
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/28429
dc.language.isoengspa
dc.publisherEngineering in Medicine and Biology Societyspa
dc.relation.citationTitleIEEE Engineering in Medicine and Biology Society
dc.relation.ispartofIEEE Engineering in Medicine and Biology Society, ISSN: 1558-4615; EISSN: 1094-687X (2014)spa
dc.relation.urihttps://ieeexplore.ieee.org/abstract/document/6944552spa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourceIEEE Engineering in Medicine and Biology Societyspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordHemodynamicsspa
dc.subject.keywordPediatricsspa
dc.subject.keywordHemorrhagingspa
dc.subject.keywordBloodspa
dc.subject.keywordUltrasonic variables measurementspa
dc.subject.keywordCouplingsspa
dc.subject.keywordSpectroscopyspa
dc.titleDifferences in the cerebral hemodynamics regulation mechanisms of premature infants with intra-ventricular hemorrhage assessed by means of phase rectified signal averagingspa
dc.title.TranslatedTitleDiferencias en los mecanismos de regulación de la hemodinámica cerebral de los prematuros con hemorragia intraventricular evaluados mediante promediado de señales de rectificación de fasespa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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