Ítem
Solo Metadatos

Delayed-type hypersensitivity and lymphocyte proliferation in response to leishmania major infection in a group of children in jericho

Mostrar el registro sencillo de la publicación
dc.creatorAlvarado , Ricardospa
dc.creatorEnk, Claesspa
dc.creatorJabel, Kamalspa
dc.creatorSchnur, Lionelspa
dc.creatorFrankenburg, Shoshanaspa
dc.date.accessioned2020-08-06T16:20:14Z
dc.date.available2020-08-06T16:20:14Z
dc.date.created1989-04spa
dc.description.abstractThe cellular response to Leishmania major was evaluated in vitro with a lymphocyte proliferation microtest, performed on 100 ?l of whole blood obtained by finger prick. The maximum time and optimum conditions for storage of fresh blood before testing were determined, and the ability of the assay to evaluate cellular immunity to Leishmania was compared to that of the classical Montenegro skin test. A positive correlation between the diameter of the skin induration and the stimulation index was demonstrated. Defining a positive skin test by induration ?5 mm, and a positive proliferation assay by a stimulation index >2·6 and a response ?3000 ct/min, we found a significant correlation between the 2 tests. The proliferation assay was less sensitive than the skin test, but somewhat more specific. Diagnostic specificities and sensitivities did not differ for the 2 tests.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/0035-9203(89)90637-8
dc.identifier.issnISSN: 0035-9203
dc.identifier.issnEISSN: 1878-3503
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/25929
dc.language.isoengspa
dc.publisherElsevierspa
dc.relation.citationEndPage192
dc.relation.citationIssueNo. 2
dc.relation.citationStartPage189
dc.relation.citationTitleTransactions of the Royal Society of Tropical Medicine and Hygiene
dc.relation.citationVolumeVol. 83
dc.relation.ispartofTransactions of the Royal Society of Tropical Medicine and Hygiene, ISSN: 0035-9203; EISSN: 1878-3503, Vol.83, No.2 (1989-04); pp.189-192spa
dc.relation.urihttps://academic.oup.com/trstmh/article-abstract/83/2/189/1939167?redirectedFrom=fulltextspa
dc.rights.accesRightsinfo:eu-repo/semantics/closedAccess
dc.rights.accesoBloqueado (Texto referencial)spa
dc.sourceTransactions of the Royal Society of Tropical Medicine and Hygienespa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordLeishmaniaspa
dc.subject.keywordProliferationspa
dc.titleDelayed-type hypersensitivity and lymphocyte proliferation in response to leishmania major infection in a group of children in jerichospa
dc.title.TranslatedTitleHipersensibilidad de tipo tardío y proliferación de linfocitos en respuesta a la infección mayor por leishmania en un grupo de niños en Jericóspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
Archivos
Colecciones
Artículos