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Sternal osteomyelitis and scrofuloderma due to BCG vaccination

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dc.creatorCorrales I.F.spa
dc.creatorCortés J.A.spa
dc.creatorMesa M.L.spa
dc.creatorZamora G.spa
dc.date.accessioned2020-05-26T00:02:49Z
dc.date.available2020-05-26T00:02:49Z
dc.date.created2003spa
dc.description.abstractBCG vaccine has been used for nearly 100 years in the prevention of tuberculosis. The case of a 13 month-old girl vaccinated as a newborn with BCG is described as presenting a sternal mass with associated periostic erosion. The mass was resected, and histopathological examination revealed a chronic inflammatory reaction with caseous granulomas, and extension to bone and skin. PCR amplifications using specific primers for Mycobacterium tuberculosis on paraffin-embedded tissue were negative. BCG vaccination at birth, the histological appearance and the absence of M. tuberculosis DNA in the resected tissue indicated that osteomyelitis and scrofuloderma were a consequence of BCG. Osteomyelitis is a rarely occurring adverse effect of BCG vaccination, more commonly seen in immunosuppressed patients. In the patient described above, no symptoms of immunodeficiency were seen, however.eng
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23529
dc.language.isoengspa
dc.relation.citationEndPage207
dc.relation.citationIssueNo. 2
dc.relation.citationStartPage202
dc.relation.citationTitleBiomédica : revista del Instituto Nacional de Salud
dc.relation.citationVolumeVol. 23
dc.relation.ispartofBiomédica : revista del Instituto Nacional de Salud, Vol.23, No.2 (2003); pp. 202-207spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-0142030004&partnerID=40&md5=b18e36f8fd83d0c306d94d37567ceeefspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordBacterial DNAspa
dc.subject.keywordBCG vaccinespa
dc.subject.keywordArticlespa
dc.subject.keywordCase reportspa
dc.subject.keywordFemalespa
dc.subject.keywordGeneticsspa
dc.subject.keywordHumanspa
dc.subject.keywordInfantspa
dc.subject.keywordIsolation and purificationspa
dc.subject.keywordMicrobiologyspa
dc.subject.keywordMycobacterium tuberculosisspa
dc.subject.keywordOsteomyelitisspa
dc.subject.keywordPathologyspa
dc.subject.keywordPolymerase chain reactionspa
dc.subject.keywordSkin tuberculosisspa
dc.subject.keywordSternumspa
dc.subject.keywordTuberculous arthritisspa
dc.subject.keywordVaccinationspa
dc.subject.keywordBCG Vaccinespa
dc.subject.keywordDNAeng
dc.subject.keywordFemalespa
dc.subject.keywordHumansspa
dc.subject.keywordInfantspa
dc.subject.keywordMycobacterium tuberculosisspa
dc.subject.keywordOsteomyelitisspa
dc.subject.keywordPolymerase Chain Reactionspa
dc.subject.keywordSternumspa
dc.subject.keywordTuberculosiseng
dc.subject.keywordTuberculosiseng
dc.subject.keywordVaccinationspa
dc.titleSternal osteomyelitis and scrofuloderma due to BCG vaccinationspa
dc.title.TranslatedTitleOsteomielitis esternal y escrofuloderma por vacuna BCG.spa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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