Ítem
Embargo
Hiperparatiroidismo post-trasplante renal en Colombia: Prevalencia a cinco años y factores asociados
Título de la revista
Autores
Mendoza Olmos, Elkin Jose
Montero Cetina, Camilo
Torres Serrano, Rodolfo
Cotés Palacio, Katherinne
Fecha
2025-02-15
Directores
Hernández Herrera, Gilma Norela
ISSN de la revista
Título del volumen
Editor
Universidad del Rosario
Universidad CES. Facultad de Medicina
Universidad CES. Facultad de Medicina
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Resumen
Estudio de corte transversal retrospectivo en población trasplantada renal, donde se evalua el hiperparatiroidismo al quinto año de trasplante y se exploran factores asociados al desenlace. Se revisan 778 pacientes de los cuales cumplen criterios de inclusión 176. De estos se revisan variables sociodemograficas de interes con descripcion de prevalencia de hiperparatiroidismo a los cinco años post trasplante del 11,9%. Se exploran posibles factores asociados al desenlace, encontrando que la edad y el peso generan tendencia al desenlace. Se realiza analisis multivariado ajustado por edad peso sexo y tasa de filtracion glomerular categorizada en menores de 60 ml min 1.73 m2 o no, evidenciando relacion del peso con el hiperparatiroidismo a los cinco años post trasplante (OR 1,05; IC95%: 0,99-1,09; p=0,057), otras variables no se evidencia relacion significativa.
Abstract
Introduction: Kidney transplant is the only current intervention that replaces kidney function. One of the main non-immune-mediated complications in transplantation is alterations in bone mineral metabolism. Post-transplant hyperparathyroidism is one of them. Methods: Analytical cross-sectional observational study, carried out in kidney transplant patients from August 2007 to December 2019 in three kidney transplant programs in Colombia. The frequency of hyperparathyroidism 5 years after kidney transplant is described, and factors associated with this alteration are analyzed. Results: A total of 176 patients were analyzed. The prevalence of hyperparathyroidism in the fifth year after transplantation was 11.9%. Variables such as sex, weight, age of the recipient at the time of evaluation, stage of chronic kidney disease (CKD), etiology of CKD and glomerular filtration rate were evaluated. Weight was the variable that most explained the outcome OR 1.05 (95% CI 0.99 – 1.09 p=0.057) Conclusions: The prevalence of hyperparathyroidism in kidney transplant patients at the fifth year is lower than that reported in other studies. The main factor associated with its development in our study was weight.
Palabras clave
Hiperparatiroidismo , Trasplante de riñon , Factores asociados
Keywords
Hyperparathyroidism , Kidney transplantation
