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Sporozoite and liver stage antigen plasmodium falciparum peptides bind specifically to human hepatocytes

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dc.creatorPuentes, Alvarospa
dc.creatorGarcía, Javierspa
dc.creatorVera, Ricardospa
dc.creatorLópez, Ramsésspa
dc.creatorSuarez, Jorgespa
dc.creatorRodríguez, Luisspa
dc.creatorCurtidor, Hernandospa
dc.creatorOcampo, Marisol
dc.creatorTovar, Dianaspa
dc.creatorForero, Marthaspa
dc.creatorBermudez, Adrianaspa
dc.creatorCortes, Jimenaspa
dc.creatorUrquiza, Mauriciospa
dc.creatorPatarroyo, Manuel E.spa
dc.date.accessioned2020-08-19T14:40:42Z
dc.date.available2020-08-19T14:40:42Z
dc.date.created2004-03-12spa
dc.description.abstractSporozoite and Liver Stage Antigen (SALSA) sequence synthetic peptides were used in HepG2 cell binding assays to identify regions involved in parasite invasion. SALSA 20608 () and 20611 () peptides were determined as having high binding activity in HepG2 cell assays, some of them were located in immunogenic regions. Immune-fluorescence antibody test with 24276 (20608 peptide analogue, CGIWSKDEKAQGEESHCG) showed sporozoite and merozoite reactivity. This data suggests SALSA high activity binding peptides’ (HABPs) possible role in hepatic cell invasion and merozoite invasion of erythrocytes.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.vaccine.2003.09.029
dc.identifier.issnISSN: 0264-410X
dc.identifier.issnEISSN: 1873-2518
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/26992
dc.language.isoengspa
dc.publisherThe Japanese Society for Vaccinologyspa
dc.publisherElsevierspa
dc.relation.citationEndPage1156
dc.relation.citationIssueNo. 9-10
dc.relation.citationStartPage1150
dc.relation.citationTitleVaccine
dc.relation.citationVolumeVol. 22
dc.relation.ispartofVaccine, ISSN: 0264-410X;EISSN: 1873-2518, Vol.22, No.9-10 (2004); pp. 1150-1156spa
dc.relation.urihttps://www.sciencedirect.com/science/article/pii/S0264410X03006972?via%3Dihubspa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourceVaccinespa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordPlasmodium falciparumspa
dc.subject.keywordSALSA proteinspa
dc.subject.keywordBinding peptidesspa
dc.subject.keywordCritical residuesspa
dc.subject.keywordHepatocyte binding peptidesspa
dc.titleSporozoite and liver stage antigen plasmodium falciparum peptides bind specifically to human hepatocytesspa
dc.title.TranslatedTitleLos péptidos de plasmodium falciparum del antígeno de la etapa hepática y del esporozoito se unen específicamente a los hepatocitos humanosspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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