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Solo Metadatos
Use of intrathecal baclofen administered by programmable infusion pumps in resistent spasticity.
| dc.creator | Broseta, J. | spa |
| dc.creator | Morales, F. | spa |
| dc.creator | Garcia, G. | spa |
| dc.creator | Sanchez Ledesma, M. J. | spa |
| dc.creator | Anaja, J. | spa |
| dc.creator | Gonzalez Darder, J. | spa |
| dc.creator | Barberá, J. | spa |
| dc.date.accessioned | 2020-08-19T14:41:13Z | |
| dc.date.available | 2020-08-19T14:41:13Z | |
| dc.date.created | 1989 | spa |
| dc.description.abstract | On the basis of previous experimental and clinical studies1,2 patients with severe spasticity due to spinal cord damage from multiple sclerosis in 8 cases and postraumatic paraplegia in 6 and resistent to all conservative treatments were selected for a trial with morphine and baclofen administered intrathecally through a catheter placed in the spinal subarachnoid space rostral to the affected segments and attached to a subcutaneous reservoir. Whereas morphine single injection did not show any benefit, baclofen bolus injection 30 to 60 ?g, revealed a marked decrease of spasticity and associated symptoms in 8 cases. After checking the clinical effect during 3 weeks and changes in electroneurophysiological studies and bladder manometry the catheter was attached to a subcutaneous programmable pump able to be refilled percutaneously and administered baclofen continuously or more often following a multistep complex programme in total doses of 90 to 150 ?g per day. After a mean follow-up of 5 months all cases showed an absence of spasms and pain, a notable improvement for bettering of sphincter functions and a marked muscle relaxation that improves motor capacity, leading to increased ambulation or mobility. Neither complications nor side-effects were observed. | eng |
| dc.format.mimetype | application/pdf | |
| dc.identifier.doi | https://doi.org/10.1007/978-3-7091-9029-6_9 | |
| dc.identifier.issn | ISSN: 0065-1419 | |
| dc.identifier.issn | EISSN: 2197-8395 | |
| dc.identifier.issn | ISBN: 978-3-7091-9031-9 | |
| dc.identifier.issn | EISBN: 978-3-7091-9029-6 | |
| dc.identifier.uri | https://repository.urosario.edu.co/handle/10336/27170 | |
| dc.language.iso | eng | spa |
| dc.publisher | Springer Nature | spa |
| dc.relation.citationEndPage | 45 | |
| dc.relation.citationStartPage | 39 | |
| dc.relation.citationTitle | Acta Neurochirurgica;Acta Neurochirurgica. Supplementum: Advances in Stereotactic and Functional Neurosurgery 8 | |
| dc.relation.citationVolume | Vol. 46 | |
| dc.relation.ispartof | Acta Neurochirurgica, Supplement, ISSN: 0065-1419; EISSN: 2197-8395, Vol.46 (1989);pp. 39-45 | spa |
| dc.relation.ispartof | Acta Neurochirurgica. Supplementum: Advances in Stereotactic and Functional Neurosurgery 8, ISBN: 978-3-7091-9031-9 ; EISBN: 978-3-7091-9029-6, Supl.46 (1989); pp. 39-45 | spa |
| dc.relation.uri | https://link.springer.com/chapter/10.1007%2F978-3-7091-9029-6_9 | spa |
| dc.rights.accesRights | info:eu-repo/semantics/restrictedAccess | |
| dc.rights.acceso | Restringido (Acceso a grupos específicos) | spa |
| dc.source | Acta Neurochirurgica | spa |
| dc.source | Acta Neurochirurgica. Supplementum: Advances in Stereotactic and Functional Neurosurgery 8 | spa |
| dc.source.instname | instname:Universidad del Rosario | |
| dc.source.reponame | reponame:Repositorio Institucional EdocUR | |
| dc.subject.keyword | Spasticity | spa |
| dc.subject.keyword | Intrathecal | spa |
| dc.subject.keyword | Baclofen | spa |
| dc.subject.keyword | Infusion pump | spa |
| dc.title | Use of intrathecal baclofen administered by programmable infusion pumps in resistent spasticity. | spa |
| dc.title.TranslatedTitle | Uso de baclofeno intratecal administrado por bombas de infusión programables en espasticidad resistente. | spa |
| dc.type | article | eng |
| dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | |
| dc.type.spa | Artículo | spa |



