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Guillain-Barré syndrome in Colombia: where do we stand now?

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dc.creatorMahecha, María P.spa
dc.creatorOjeda, Ernestospa
dc.creatorVega, Daniel A.spa
dc.creatorSarmiento Monroy, Juan C.spa
dc.creatorAnaya, Juan-Manuel
dc.date.accessioned2020-08-19T14:43:54Z
dc.date.available2020-08-19T14:43:54Z
dc.date.created2016-07-15spa
dc.description.abstractGuillain–Barre´ syndrome (GBS) is a rapid-onset muscle weakness disease caused by the immune-mediated damage of the peripheral nervous system. Since there is an increase incidence of GBS cases in Latin America, particularly in Colombia, and most of them are currently preceded by Zika virus (ZIKV) infection, we aimed to assess the available evidence of the disease in Colombia through a systematic literature review. Out of 51 screened abstracts, only 16 corresponded to articles that met inclusion criteria, of which 15 were case reports or case series. A total of 796 cases of GBS were reported in the included articles. The majority of patients were males (66.8 %) and younger than 50 years old (94 %). An infectious disease before the onset of GBS was registered in 31 % of patients, with gastrointestinal or respiratory symptoms being the most frequently observed. In those cases in which electrodiagnostic tests were performed, the most common subphenotype was acute inflammatory demyelinating polyneuropathy (17 %). Death was reported in 15 % of patients. Data regarding GBS in Colombia is scant and heterogeneous. Taking into account the burden of the disease and the recent rise of GBS cases associated with ZIKV, a careful patient evaluation and a systematic collection of data are warranted. A form to data gathering is proposed.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1007/s12026-016-8816-8
dc.identifier.issnISSN: 0257-277X
dc.identifier.issnEISSN: 1559-0755
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/27791
dc.language.isoengspa
dc.publisherSpringer Naturespa
dc.relation.citationEndPage81
dc.relation.citationStartPage72
dc.relation.citationTitleImmunologic Research
dc.relation.citationVolumeVol. 65
dc.relation.ispartofImmunologic Research, ISSN: 0257-277X; EISSN: 1559-0755, Vol.65 (2017); pp. 72–81spa
dc.relation.urihttps://link.springer.com/content/pdf/10.1007/s12026.016.8816.8spa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourceImmunologic Researchspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordGuillain–Barre´ syndromespa
dc.subject.keywordZika virusspa
dc.subject.keywordAnti-gangliosides antibodiesspa
dc.subject.keywordLatin Americaspa
dc.titleGuillain-Barré syndrome in Colombia: where do we stand now?spa
dc.title.TranslatedTitleSíndrome de Guillain-Barré en Colombia: ¿dónde estamos ahora?spa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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