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A review of blood diseases and cytopenias associated with human parvovirus B19 infection

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dc.creatorKerr, Jonathan R.spa
dc.date.accessioned2020-05-25T23:58:56Z
dc.date.available2020-05-25T23:58:56Z
dc.date.created2015spa
dc.description.abstractParvovirus B19 is a single-stranded DNA virus which preferentially targets the erythroblast resulting in red cell aplasia, which is temporary in immunocompetent persons. Since the discovery of B19 virus in 1975, a wide variety of blood diseases and cytopenias affecting several blood cell lineages have been documented during or following B19 infection. These include cytopenias affecting the erythroid, megakaryoblastoid, myeloid and lymphoid lineages, as well as a variety of bicytopenias, pancytopenia, bone marrow necrosis / fat embolism syndrome, myelodysplastic syndrome, leucoerythroblastopenia, and hemophagocytic lymphohistiocytosis. B19 infection may also complicate and precede the course of acute leukemia, the significance of which remains to be determined. This review describes the current state of knowledge of the abnormalities of individual blood cell lineages encountered during parvovirus B19 infection, over the almost 40years since its discovery, and reveals some very interesting themes, which improve our understanding of the pathogenesis of B19 infection with particular reference to the bone marrow. © 2015 John Wiley and Sons, Ltd.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1002/rmv.1839
dc.identifier.issn10529276
dc.identifier.issn10991654
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/22952
dc.language.isoengspa
dc.publisherJohn Wiley and Sons Ltdspa
dc.relation.citationEndPage240
dc.relation.citationIssueNo. 4
dc.relation.citationStartPage224
dc.relation.citationTitleReviews in Medical Virology
dc.relation.citationVolumeVol. 25
dc.relation.ispartofReviews in Medical Virology, ISSN:10529276, 10991654, Vol.25, No.4 (2015); pp. 224-240spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84935748846&doi=10.1002%2frmv.1839&partnerID=40&md5=96ec3ab925a66563eae364d28c626c23spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordHemoglobinspa
dc.subject.keywordhumaneng
dc.subject.keywordImmunoglobulin mspa
dc.subject.keywordAntigen antibody complexspa
dc.subject.keywordAplastic anemiaspa
dc.subject.keywordArthralgiaspa
dc.subject.keywordArthritisspa
dc.subject.keywordBone marrowspa
dc.subject.keywordBone marrow necrosisspa
dc.subject.keywordCell lineagespa
dc.subject.keywordChillspa
dc.subject.keywordCytopeniaspa
dc.subject.keywordDna repairspa
dc.subject.keywordErythema infectiosumspa
dc.subject.keywordErythrophagocytosisspa
dc.subject.keywordGranulocytespa
dc.subject.keywordHeadachespa
dc.subject.keywordHematologic diseasespa
dc.subject.keywordHemophagocytic syndromespa
dc.subject.keywordHumanspa
dc.subject.keywordHuman parvovirus b19spa
dc.subject.keywordImmunologyspa
dc.subject.keywordLymphocytespa
dc.subject.keywordMacrophagespa
dc.subject.keywordMegakaryocytespa
dc.subject.keywordMonocytespa
dc.subject.keywordMyalgiaspa
dc.subject.keywordMyelodysplastic syndromespa
dc.subject.keywordMyelophthisic anemiaspa
dc.subject.keywordNeutrophilspa
dc.subject.keywordNonhumanspa
dc.subject.keywordPathogenesisspa
dc.subject.keywordPetechiaspa
dc.subject.keywordPruritusspa
dc.subject.keywordRashspa
dc.subject.keywordReticulocytespa
dc.subject.keywordReviewspa
dc.subject.keywordTemperaturespa
dc.subject.keywordThrombocytespa
dc.subject.keywordThrombocytopeniaspa
dc.subject.keywordVirus excretionspa
dc.subject.keywordVirus replicationspa
dc.subject.keywordComplicationspa
dc.subject.keywordHematologic diseasespa
dc.subject.keywordIsolation and purificationspa
dc.subject.keywordParvovirus infectionspa
dc.subject.keywordVirologyspa
dc.subject.keywordHematologic diseasesspa
dc.subject.keywordHumansspa
dc.subject.keywordParvoviridae infectionsspa
dc.subject.keywordParvovirus b19eng
dc.titleA review of blood diseases and cytopenias associated with human parvovirus B19 infectionspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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