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Reply to: Skin moisturization for xerosis related to targeted anticancer therapies

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dc.creatorValentine, Johannahspa
dc.creatorReddy Belum, Viswanathspa
dc.creatorDuran, Juanitaspa
dc.creatorCiccolini, Kathrynspa
dc.creatorSchindler, Katjaspa
dc.creatorWu, Shenhongspa
dc.creatorLacouture, Mario E.spa
dc.date.accessioned2020-08-06T16:20:21Z
dc.date.available2020-08-06T16:20:21Z
dc.date.created2015spa
dc.description.abstractTo the Editor: We would like to thank Drs Gisondi and Girolomoni for their comments regarding the treatment of xerosis. We agree that salicylic acid and ammonium lactate should be used judiciously, and only on areas of hyperkeratosis without evident dermatitis, as is commonly seen in patients treated with targeted therapies. Indeed, targeted therapies lead to aberrant keratinocyte proliferation, migration, differentiation, and adhesion, all of which result in xerotic skin with retention hyperkeratosis.1 Patients receiving targeted therapies who develop xerosis and hyperkeratosis require rapid resolution of findings, because progression into a grade 3 adverse event dictates interruption, dose decrease, or discontinuation of life-prolonging anticancer treatments. Therefore, according to the treatment algorithm in Fig 4 of our manuscript, salicylic acid or ammonium lactate is to be used in conjunction with emollients and topical steroids to eczematous areas.2 These treatment recommendations are based on clinical experience at a dermatology referral clinic for patients on targeted therapies started in 2006.3eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.jaad.2015.03.038
dc.identifier.issnISSN: 0190-9622
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/25970
dc.language.isoengspa
dc.publisherElsevierspa
dc.publisherMosbyspa
dc.relation.citationEndPagee36
dc.relation.citationIssueNo. 1
dc.relation.citationStartPagee35
dc.relation.citationTitleJournal of the American Academy of Dermatology
dc.relation.citationVolumeVol. 73
dc.relation.ispartofJournal of the American Academy of Dermatology, ISSN: 0190-9622, Vol.73, No.1 (July, 2015); pp.e35-e36spa
dc.relation.urihttps://www.jaad.org/article/S0190-9622(15)01482-6/fulltext#%20spa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourceJournal of the American Academy of Dermatologyspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordAntineoplastic agentspa
dc.subject.keywordAntineoplastic agentspa
dc.subject.keywordEnzyme inhibitorspa
dc.subject.keywordMonoclonal antibodyspa
dc.subject.keywordEczemaspa
dc.subject.keywordHumanspa
dc.subject.keywordHyperkeratosisspa
dc.subject.keywordIncidencespa
dc.subject.keywordKeratinocytespa
dc.subject.keywordLetterspa
dc.subject.keywordMoisturespa
dc.subject.keywordMolecularly targeted therapyspa
dc.subject.keywordPriority journalspa
dc.subject.keywordSkin functionspa
dc.subject.keywordSkin moisturizationspa
dc.subject.keywordXerosisspa
dc.subject.keywordAdverse effectsspa
dc.subject.keywordChemically inducedspa
dc.subject.keywordMolecularly targeted therapyspa
dc.subject.keywordNeoplasmsspa
dc.subject.keywordSkin diseasespa
dc.subject.keywordAntibodiesspa
dc.subject.keywordmonoclonalspa
dc.subject.keywordAntibodiesspa
dc.subject.keywordmonoclonalspa
dc.subject.keywordAntineoplastic agentsspa
dc.subject.keywordAntineoplastic agentsspa
dc.subject.keywordEnzyme inhibitorsspa
dc.subject.keywordEnzyme inhibitorsspa
dc.subject.keywordHumansspa
dc.subject.keywordHumansspa
dc.subject.keywordMolecular targeted therapyspa
dc.subject.keywordMolecular targeted therapyspa
dc.subject.keywordNeoplasmsspa
dc.subject.keywordNeoplasmsspa
dc.subject.keywordSkin diseasesspa
dc.subject.keywordSkin diseasesspa
dc.titleReply to: Skin moisturization for xerosis related to targeted anticancer therapiesspa
dc.title.alternativeReply to: 'Skin moisturization for xerosis related to targeted anticancer therapies'spa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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