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Sleep apnea: Tracking effects of a first session of CPAP therapy by means of Granger causality

dc.creatorOrjuela Cañón, Alvaro Davidspa
dc.creatorCerquera, Alexanderspa
dc.creatorFreund, Jan A.spa
dc.creatorJuliá-Serdá, Gabrielspa
dc.creatorRavelo-García, Antonio G.spa
dc.date.accessioned2020-05-26T00:05:13Z
dc.date.available2020-05-26T00:05:13Z
dc.date.created2020spa
dc.description.abstractConnectivity between physiological networks is an issue of particular importance for understanding the complex interaction brain-heart. In the present study, this interaction was analyzed in polysomnography recordings of 28 patients diagnosed with obstructive sleep apnea (OSA) and compared with a group of 10 control subjects. Electroencephalography and electrocardiography signals from these polysomnography time series were characterized employing Granger causality computation to measure the directed connectivity among five brain waves and three spectral subbands of heart rate variability. Polysomnography data from OSA patients were recorded before and during a first session of continuous positive air pressure (CPAP) therapy in a split-night study. Results showed that CPAP therapy allowed the recovery of inner brain connectivities, mainly in subsystems involving the theta wave. In addition, differences between control and OSA patients were established in connections that involve lower frequency ranges of heart rate variability. This information can be potentially useful in the initial diagnosis of OSA, and determine the role of cardiac activity in sleep dynamics based on the use of three subbands of heart rate variability. © 2019 Elsevier B.V.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.cmpb.2019.105235
dc.identifier.issn1692607
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23767
dc.language.isoengspa
dc.publisherElsevier Ireland Ltdspa
dc.relation.citationTitleComputer Methods and Programs in Biomedicine
dc.relation.citationVolumeVol. 187
dc.relation.ispartofComputer Methods and Programs in Biomedicine, ISSN:1692607, Vol.187,(2020)spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85075822713&doi=10.1016%2fj.cmpb.2019.105235&partnerID=40&md5=8129e1495027b0422eb01e0a4ac5c5d8spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAtmospheric pressurespa
dc.subject.keywordElectroencephalographyspa
dc.subject.keywordElectrophysiologyspa
dc.subject.keywordPatient monitoringspa
dc.subject.keywordPatient treatmentspa
dc.subject.keywordSleep researchspa
dc.subject.keywordStatistical testsspa
dc.subject.keywordAir pressuresspa
dc.subject.keywordBrain connectivityspa
dc.subject.keywordCardiac activityspa
dc.subject.keywordGranger Causalityspa
dc.subject.keywordHeart rate variabilityspa
dc.subject.keywordLower frequenciesspa
dc.subject.keywordObstructive sleep apneaspa
dc.subject.keywordTracking effectsspa
dc.subject.keywordHeartspa
dc.subject.keywordAdultspa
dc.subject.keywordAgedspa
dc.subject.keywordArticlespa
dc.subject.keywordCausalityspa
dc.subject.keywordClinical articlespa
dc.subject.keywordElectrocardiographyspa
dc.subject.keywordElectroencephalogramspa
dc.subject.keywordElectroencephalographyspa
dc.subject.keywordFemalespa
dc.subject.keywordHeart rate variabilityspa
dc.subject.keywordHumanspa
dc.subject.keywordMalespa
dc.subject.keywordPolysomnographyspa
dc.subject.keywordPositive end expiratory pressurespa
dc.subject.keywordRetrospective studyspa
dc.subject.keywordSleep disordered breathingspa
dc.subject.keywordTheta rhythmspa
dc.subject.keywordBrain-heart networkspa
dc.subject.keywordContinuous positive air pressurespa
dc.subject.keywordPhysiological couplingspa
dc.titleSleep apnea: Tracking effects of a first session of CPAP therapy by means of Granger causalityspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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