Ítem
Acceso Abierto

Airborne culprits: A comprehensive review of PM, silica, and TCDD in autoimmune diseases

Mostrar el registro sencillo de la publicación
dc.creatorGaleano-Sanchez, Danielspa
dc.creatorMorales-González, Victoriaspa
dc.creatorMonsalve Carmona, Diana Marcelaspa
dc.creatorRamírez Santana, Heily Carolinaspa
dc.creatorAcosta Ampudia, Yeny Yasbleidy spa
dc.date.accessioned2025-01-26T18:29:58Z
dc.date.available2025-01-26T18:29:58Z
dc.date.created2024-12-01spa
dc.date.issued2024-12-01spa
dc.descriptionAutoimmune diseases (ADs) are immunological disorders arising from the breakdown of immune tolerance, influenced by various internal and external factors. Persistent exposure to environmental factors, particularly air pollution, is linked to systemic inflammation, oxidative stress, and apoptosis, which contribute to the development of ADs. This review examines the impact of air pollutants, including particulate matter, silica, and TCDD, by analyzing epidemiological studies, animal models, and in vitro assays. It focuses on how air pollution disrupts the immune system, leading to apoptosis, increased oxidative stress, cytokine production, autoantigen release, autoantibody production, and autoreactivity, which are particularly significant in ADs like rheumatoid arthritis, systemic lupus erythematosus, Sjögren's syndrome, and systemic sclerosis. In essence, this approach aims to provide a profound understanding of how exposure to air pollution can initiate or contribute to ADs, offering potential avenues for more targeted preventive and therapeutic strategies.spa
dc.format.mimetypeapplication/pdfspa
dc.identifier.doihttps://doi.org/10.1016/j.jtauto.2024.100253spa
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/44808
dc.language.isoengspa
dc.publisherJournal of Translational Autoimmunityspa
dc.relation.ispartofJournal of Translational Autoimmunityspa
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccessspa
dc.rights.accesoAbierto (Texto Completo)spa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/spa
dc.sourceJournal of Translational Autoimmunityspa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectAutoimmune diseasesspa
dc.subjectAir pollutionspa
dc.subjectInflammationspa
dc.subjectParticulate matterspa
dc.subjectSilicaspa
dc.subjectTCDDspa
dc.subjectEnvironmentspa
dc.titleAirborne culprits: A comprehensive review of PM, silica, and TCDD in autoimmune diseasesspa
dc.typearticlespa
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersionspa
dc.type.spaArtículospa
Archivos
Bloque original
Mostrando1 - 1 de 1
Miniatura
Nombre:
Airborne_culprits_A_comprehensive_review_of_PM_silica_and_TCDD_in.pdf
Tamaño:
3.06 MB
Formato:
Adobe Portable Document Format
Descripción:
Descargar
Colecciones
Artículos