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Uso de lisados bacterianos en la prevención de la infección respiratoria recurrente en pediatría. Revisión sistemática de la literatura

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dc.contributor.advisorOlmos, Carlos
dc.contributor.advisorJagua, Andrés
dc.creatorRodriguez Ossa, Sandra Patricia
dc.creatorAguilera Martinez, Sara
dc.creator.degreeEspecialista en Pediatría
dc.date.accessioned2013-01-30T19:43:30Z
dc.date.available2013-01-30T19:43:30Z
dc.date.created2012-11-30
dc.date.issued2012
dc.descriptionLas infecciones respiratorias altas y bajas son una causa común de morbimortalidad infantil. Se ha propuesto el uso de los lisados bacterianos para prevenir las infecciones recurrentes sin embargo su uso aún se considera controversial. Metodología: Se realizó una revisión sistemática de la literatura. La búsqueda se realizó a través de las bases de datos PUBMED, Embase, Ovid, LiLaCS y Cochrane library plus. Se incluyeron metanálisis publicados en idiomas inglés y español, entre los años 1998 y 2012. Se realizó una evaluación de calidad siguiendo la estrategia Quorum y un análisis cualitativo y cuantitativo de los resultados. Resultados: Se incluyeron 4 revisiones sistemáticas de la literatura con metanálisis. Fue apreciable la disminución de las recurrencias de las infecciones respiratorias relacionadas con el uso de los lisados bacterianos. Los lisados bacterianos disminuyen la necesidad de uso de antibióticos. No se encontró evidencia sobre el uso de los lisados sobre desenlaces como la necesidad de intervenciones adicionales, tiempo de hospitalización, costo relacionado con la atención en salud. No se reportaron eventos adversos de importancia. Conclusión: Los lisados bacterianos son eficaces en disminuir la recurrencia de las infecciones respiratorias en pacientes en edad pediátrica.spa
dc.description.abstractThe upper and lower respiratory infections are a common cause of childhood morbidity and mortality. It has proposed the use of bacterial lysates to prevent recurrent infections even though their use is considered controversial. Methodology: We conducted a systematic review of the literature. The search was performed using the databases PubMed, Embase, Ovid, Lilacs and Cochrane Library. We included meta-analyzes published in English and Spanish, between 1998 and 2012. An evaluation of quality following the strategy Quorum and qualitative and quantitative analysis of the results. Results: We included 4 systematic reviews of the literature with meta-analysis. Was appreciably reduced recurrences of respiratory infections related to the use of bacterial lysates. The bacterial lysates reduce the need for antibiotics. There was no evidence on the use of the lysates on outcomes such as the need for additional interventions, length of stay, costs related to health care. There were no significant adverse events. Conclusion: The bacterial lysates are effective in reducing the recurrence of respiratory infections in pediatric patients.eng
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dc.format.tipoDocumentospa
dc.identifier.doihttps://doi.org/10.48713/10336_4150
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/4150
dc.language.isospa
dc.publisherUniversidad del Rosariospa
dc.publisher.departmentFacultad de medicinaspa
dc.publisher.programEspecialización en Pediatríaspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
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dc.rights.ccAtribución-NoComercial-SinDerivadas 2.5 Colombiaspa
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dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
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dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectLisado bacterianospa
dc.subjectniñosspa
dc.subjectinfecciones respiratoriasspa
dc.subjectprevención y controlspa
dc.subjectrevisión sistemáticaspa
dc.subject.keywordBacterial lysateeng
dc.subject.keywordchildreneng
dc.subject.keywordrespiratory infectioneng
dc.subject.keywordprevention and controleng
dc.subject.keywordsystematic revieweng
dc.subject.lembAdyuvantes inmunológicos::Uso Terapéuticospa
dc.subject.lembEnfermedades respiratorias pediátricasspa
dc.subject.lembInfecciones respiratorias en niños::Tratamientospa
dc.titleUso de lisados bacterianos en la prevención de la infección respiratoria recurrente en pediatría. Revisión sistemática de la literaturaspa
dc.typemasterThesiseng
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaTrabajo de gradospa
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