Ítem
Solo Metadatos

Central nervous system compromise in primary Sjögren's syndrome

Mostrar el registro sencillo de la publicación
dc.creatorAnaya, Juan-Manuel
dc.creatorVilla, Luis Aspa
dc.creatorRestrepo, Lucasspa
dc.creatorMolina, Jose F.spa
dc.creatorMantilla, Rubén D.spa
dc.creatorVargas, Sergiospa
dc.date.accessioned2020-08-19T14:41:49Z
dc.date.available2020-08-19T14:41:49Z
dc.date.created2002spa
dc.description.abstractCentral nervous system (CNS) involvement in primary Sjögren’s syndrome (SS) is poorly understood, and its frequency as well as its manifestations are subjects of controversy. The current study was undertaken to determine the prevalence and the clinical and immunogenetic characteristics of CNS compromise in a well defined group of patients with primary SS. In this retrospective study, patients fulfilled the European classification criteria. Among 120 patients with primary SS, 3 (2.5%) had CNS compromise (multiple sclerosis–like illness, complicated migraine, and optic neuritis with epilepsy). The CNS involvement coincided with the onset of sicca symptoms in 1 case. All 3 patients carried the human leukocyte antigen (HLA) DQB1*0303 allele and tested positive for anti-Ro antibodies, but not for anti-cardiolipin antibodies. Although rare, CNS compromise in primary SS can be the presenting manifestation of the disease in a few cases, and may be severe and varied.eng
dc.format.mimetypeapplication/pdf
dc.identifier.issnISSN: 1076-1608
dc.identifier.issnEISSN: 1536-7355
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/27345
dc.language.isoengspa
dc.publisherJCR: Journal of Clinical Rheumatologyspa
dc.relation.citationEndPage196
dc.relation.citationIssueNo. 4
dc.relation.citationStartPage189
dc.relation.citationTitleJournal of Clinical Rheumatology
dc.relation.citationVolumeVol. 8
dc.relation.ispartofJournal of Clinical Rheumatology, ISSN: 1076-1608 ; EISSN: 1536-7355, Vol.8, No.4 (August 200); pp. 189-196spa
dc.relation.urihttps://journals.lww.com/jclinrheum/Abstract/2002/08000/Central_Nervous_System_Compromise_in_Primary.2.aspxspa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourceJournal of Clinical Rheumatologyspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordSjögren’s syndromespa
dc.subject.keywordCentral nervous systemspa
dc.subject.keywordMultiple sclerosisspa
dc.subject.keywordMigrainespa
dc.subject.keywordHuman leukocyte antigenspa
dc.subject.keywordColombiaspa
dc.titleCentral nervous system compromise in primary Sjögren's syndromespa
dc.title.TranslatedTitleCompromiso del sistema nervioso central en el síndrome de Sjögren primariospa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
Archivos
Colecciones
Artículos