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The eukaryotic genome, its reads, and the unfinished assembly

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dc.creatorMuñoz, José Fernandospa
dc.creatorGallo, Juan Estebanspa
dc.creatorMisas, Elizabethspa
dc.creatorMcEwen, Juan Guillermospa
dc.creatorClay, Oliver Keatingespa
dc.date.accessioned2020-05-26T00:08:06Z
dc.date.available2020-05-26T00:08:06Z
dc.date.created2013spa
dc.description.abstractIn recent years, readily affordable short read sequences provided by next-generation sequencing (NGS) have become longer and more accurate. This has led to a jump in interest in the utility of NGS-only approaches for exploring eukaryotic genomes. The concept of a static, 'finished' genome assembly, which still appears to be a faraway goal for many eukaryotes, is yielding to new paradigms. We here motivate an object-view concept where the raw reads are the main, fixed object, and assemblies with their annotations take a role of dynamically changing and modifiable views of that object. © 2013 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.febslet.2013.05.048
dc.identifier.issn145793
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/24056
dc.language.isoengspa
dc.relation.citationEndPage2093
dc.relation.citationIssueNo. 14
dc.relation.citationStartPage2090
dc.relation.citationTitleFEBS Letters
dc.relation.citationVolumeVol. 587
dc.relation.ispartofFEBS Letters, ISSN:145793, Vol.587, No.14 (2013); pp. 2090-2093spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84879691390&doi=10.1016%2fj.febslet.2013.05.048&partnerID=40&md5=7ccab6f6de34c006493aef54c8e5936cspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAccuracyspa
dc.subject.keyworddnaeng
dc.subject.keywordArticlespa
dc.subject.keywordBioinformaticsspa
dc.subject.keywordFungal genomespa
dc.subject.keywordFungal strainspa
dc.subject.keywordGenome analysisspa
dc.subject.keywordHumanspa
dc.subject.keywordInformation processingspa
dc.subject.keywordInformation retrievalspa
dc.subject.keywordNext generation sequencingspa
dc.subject.keywordNonhumanspa
dc.subject.keywordPriority journalspa
dc.subject.keywordReliabilityspa
dc.subject.keywordReproducibilityspa
dc.subject.keywordSequence analysisspa
dc.subject.keywordAnimalsspa
dc.subject.keywordBase sequencespa
dc.subject.keywordChromosome mappingspa
dc.subject.keywordEukaryotaspa
dc.subject.keywordGenomeeng
dc.subject.keywordGenomicsspa
dc.subject.keywordHigh-throughput nucleotide sequencingspa
dc.subject.keywordHumansspa
dc.subject.keywordMolecular sequence annotationspa
dc.subject.keywordSequence analysiseng
dc.subject.keywordEukaryotaspa
dc.subject.keywordAssembly-free genome analysisspa
dc.subject.keywordEukaryotic genomicsspa
dc.subject.keywordMicrobial strain collectionspa
dc.subject.keywordNext generation sequencingspa
dc.subject.keywordObject-view separationspa
dc.titleThe eukaryotic genome, its reads, and the unfinished assemblyspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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