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Implementation of a training course increased the diagnosis of histoplasmosis in Colombia

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dc.creatorCaceres, Diego H.
dc.creatorZuluaga, Alejandra
dc.creatorArango-Bustamante, Karen
dc.creatorde Bedout, Catalina
dc.creatorTobón, Ángela Maria
dc.creatorRestrepo, Ángela
dc.creatorGómez, Beatriz L.
dc.creatorCano, Luz Elena
dc.creatorGonzález, Ángel
dc.creator.googleCaceres, Diego H.spa
dc.creator.googleZuluaga, Alejandraspa
dc.creator.googleArango-Bustamante, Karenspa
dc.creator.googlede Bedout, Catalinaspa
dc.creator.googleTobón, Ángela Mariaspa
dc.creator.googleRestrepo, Ángelaspa
dc.creator.googleGómez, Beatriz L.spa
dc.creator.googleCano, Luz Elenaspa
dc.creator.googleGonzález, Ángelspa
dc.date.accessioned2019-02-15T17:54:10Z
dc.date.available2019-02-15T17:54:10Z
dc.date.created2015
dc.date.issued2015
dc.description.abstractHistoplasmosis causes a significant mortality, especially persons living with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) from developing countries where access to both appropriate diagnostic methods and antiretroviral therapy are limited. A total of 81 physicians assigned to 17 Colombian departments (states) received training in the clinical, epidemiological, and diagnostic aspects of histoplasmosis. Once this training was received and during the period of October 2009-November 2012, these physicians sent biological samples for immunodiagnostic, mycological, and molecular tests from their patients with suspicion of histoplasmosis. A total of 1,536 samples from 768 patients were evaluated. Of the 768 patients studied, 463 (60%) were HIV positive, 214 (28%) HIV negative, and in 91 (12%) this diagnosis was unknown, and 538 (70%) were males. The 1,536 specimens studied comprised 722 sera, 439 blood samples, and 241 urines, which were tested by immunodiffusion (ID), culture, and antigenuria, respectively; in addition, 134 specimens were tested by performing a molecular assay. Histoplasmosis was diagnosed in 133 patients (17%). After the training, we observed more diagnoses from 27 to 44 cases per year. In this study, a significantly increased number of histoplasmosis cases reported by year were observed after implementing an educational training program. Copyright © 2015 by The American Society of Tropical Medicine and Hygiene.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doi10.4269/ajtmh.15-0108
dc.identifier.issn0002-9637
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/19087
dc.language.isoengspa
dc.relation.citationEndPage667
dc.relation.citationIssueNo. 3
dc.relation.citationStartPage662
dc.relation.citationTitleAmerican Journal of Tropical Medicine and Hygiene
dc.relation.citationVolumeVol. 93
dc.relation.ispartofAmerican Journal of Tropical Medicine and Hygiene, ISSN: 0002-9637 Vol. 93, No. 3 (2015) pp. 662-667spa
dc.relation.urihttp://www.ajtmh.org/docserver/fulltext/14761645/93/3/662.pdf?expires=1544545707&id=id&accname=guest&checksum=55D0B568F290115E17AFF8D05C0C624Bspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subjectacquired immune deficiency syndromespa
dc.subjectAjellomyces capsulatusspa
dc.subjectblood culturespa
dc.subjectdeveloping countryspa
dc.subjecteducation programspa
dc.subject.ddcEnfermedadesspa
dc.subject.keywordArticlespa
dc.subject.lembHistoplasmosisspa
dc.subject.lembSíndrome de inmunodeficienciaspa
dc.subject.lembCapacitación de empleadosspa
dc.titleImplementation of a training course increased the diagnosis of histoplasmosis in Colombiaspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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