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Cost effectiveness of strategies to combat cardiovascular disease, diabetes, and tobacco use in sub-Saharan Africa and South East Asia: mathematical modelling study.

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dc.creatorOrtegón M.spa
dc.creatorLim S.spa
dc.creatorChisholm D.spa
dc.creatorMendis S.spa
dc.date.accessioned2020-05-26T00:03:24Z
dc.date.available2020-05-26T00:03:24Z
dc.date.created2012spa
dc.description.abstractTo determine the relative costs and health effects of interventions to combat cardiovascular disease, diabetes, and tobacco related disease in order to guide the allocation of resources in developing countries. Cost effectiveness analysis of 123 single or combined prevention and treatment strategies for cardiovascular disease, diabetes, and smoking by means of a lifetime population model. Two World Health Organization sub-regions of the world: countries in sub-Saharan Africa with very high adult and high child mortality (AfrE) and countries in South East Asia with high adult and high child mortality (SearD). Demographic and epidemiological data were taken from the WHO databases of mortality and global burden of disease. Estimates of intervention coverage, effectiveness, and resource needs were drawn from clinical trials, observational studies, and treatment guidelines. Unit costs were taken from the WHO-CHOICE (Choosing Interventions that are Cost-Effective) price database. Cost per disability adjusted life year (DALY) averted, expressed in international dollars ($Int) for the year 2005. Most of the interventions studied were considered highly cost effective, meaning they generate one healthy year of life at a cost of less than $Int2000 (which is the gross domestic product per capita of the two regions considered here). Interventions that offer particularly good monetary value, and which could be considered for prioritised implementation or scale up, include demand reduction strategies of the Framework Convention for Tobacco Control ( less than $Int950 and less than $Int200 per DALY averted in AfrE and SearD respectively); combination drug therapy for people with a >25% chance of experiencing a cardiovascular event over the next decade, either alone or together with specific multidrug regimens for the secondary prevention of post-acute ischaemic heart disease and stroke ( less than $Int150 and less than $Int230 per DALY averted in AfrE and SearD respectively); and retinopathy screening and glycaemic control for patients with diabetes ( less than $Int2100 and less than $Int950 per DALY averted in AfrE and SearD respectively). This comparative economic assessment has identified a set of population-wide and individual strategies for prevention and control of cardiovascular disease that are inexpensive and cost effective in low resource settings.eng
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23589
dc.language.isoengspa
dc.relation.citationTitleBMJ (Clinical research ed.)
dc.relation.citationVolumeVol. 344
dc.relation.ispartofBMJ (Clinical research ed.), Vol.344,(2012)spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84858041945&partnerID=40&md5=925392484a2c462659b5633d28d11a9aspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAdultspa
dc.subject.keywordsoutheasterneng
dc.subject.keywordAgedspa
dc.subject.keywordArticlespa
dc.subject.keywordCardiovascular diseasespa
dc.subject.keywordCost benefit analysisspa
dc.subject.keywordDiabetes mellitusspa
dc.subject.keywordEconomicsspa
dc.subject.keywordFemalespa
dc.subject.keywordHumanspa
dc.subject.keywordMalespa
dc.subject.keywordMiddle agedspa
dc.subject.keywordSmokingspa
dc.subject.keywordSoutheast asiaspa
dc.subject.keywordTheoretical modelspa
dc.subject.keywordTobacco dependencespa
dc.subject.keywordAdultspa
dc.subject.keywordAfrica south of the saharaspa
dc.subject.keywordAgedspa
dc.subject.keywordAged, 80 and overspa
dc.subject.keywordAsiaeng
dc.subject.keywordCardiovascular diseasesspa
dc.subject.keywordCost-benefit analysisspa
dc.subject.keywordDiabetes mellitusspa
dc.subject.keywordFemalespa
dc.subject.keywordHumansspa
dc.subject.keywordMalespa
dc.subject.keywordMiddle agedspa
dc.subject.keywordModelseng
dc.subject.keywordSmokingspa
dc.subject.keywordTobacco use disorderspa
dc.titleCost effectiveness of strategies to combat cardiovascular disease, diabetes, and tobacco use in sub-Saharan Africa and South East Asia: mathematical modelling study.spa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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