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Bilateral corneal perforation and iris prolapse as a complication non-peripheral ulcerative keratitis in a patient with fulminant Granulomatosis with Polyangiitis. A case Report.

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dc.creatorVargas-Villanueva, Andrésspa
dc.creatorCarvajal-Saiz, Nataliaspa
dc.creatorMuñoz-Ortiz, Julianaspa
dc.creatorde-la-Torre, Alejandraspa
dc.date.accessioned2020-08-19T14:41:37Z
dc.date.available2020-08-19T14:41:37Z
dc.date.created2020-01-01spa
dc.description.abstractGranulomatosis with polyangiitis (GPA) (formerly known as Wegener´s granulomatosis) is a systemic necrotizing vasculitis belonging to a heterogeneous group of systemic anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis which affects small and medium-sized blood vessels [1, 2]. The annual incidence of GPA has been estimated to be 8 to 10 million, has a peak age of onset of 64 to 75 years [3], and the frequency of presentation in female and male individuals is similar [4]. Constitutional signs like fever, asthenia, and weight loss are frequent (50%) but non-specific. Ear, nose, and throat signs (crusting rhinorrhea, sinusitis, chronic otitis, or damage of the facial cartilage) are present in 70 to 100% of cases at diagnosis [5]. Lung involvement, characterized by alveolar hemorrhage or parenchymatous nodules, affects 50 to 90% of patients [4]. The focal segmental necrotizing glomerulonephritis is the most frequent renal involvement in 40 to 100% of cases [6]. Involvement of the nervous system, the central nervous system, the pachymeninges, the heart, the pericardium, and the gastrointestinal system are less frequent, observed in a range of 5 to 40% of cases [1].eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1186/s12348-020-0195-6
dc.identifier.issnISSN: 1869-5760
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/27289
dc.language.isoengspa
dc.publisherSpringer Naturespa
dc.relation.citationIssueNo. 2
dc.relation.citationTitleJournal of Ophthalmic Inflammation and Infection
dc.relation.citationVolumeVol. 10
dc.relation.ispartofJournal of Ophthalmic Inflammation and Infection, ISSN:1869-5760, Vol.10, No.2 (January, 2020); 6 pp.spa
dc.relation.urihttps://link.springer.com/article/10.1186/s12348-020-0195-6spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.sourceJournal of Ophthalmic Inflammation and Infectionspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordBilateral corneal perforationspa
dc.subject.keywordIris prolapsespa
dc.subject.keywordComplication non-peripheral ulcerativespa
dc.subject.keywordKeratitis in a patientspa
dc.subject.keywordFulminant granulomatosisspa
dc.subject.keywordPolyangiitisspa
dc.titleBilateral corneal perforation and iris prolapse as a complication non-peripheral ulcerative keratitis in a patient with fulminant Granulomatosis with Polyangiitis. A case Report.spa
dc.title.TranslatedTitlePerforación corneal bilateral y prolapso del iris como complicación de la queratitis ulcerosa no periférica en un paciente con granulomatosis fulminante con poliangeítis. Informe de un caso.spa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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