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Hyperprolactinaemia in primary Sjogren's syndrome [1]

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dc.creatorGutiérrez, M.A.spa
dc.creatorAnaya, Juan-Manuelspa
dc.creatorScopelitis E.spa
dc.creatorCitera, G.spa
dc.creatorSilveira, L. H.spa
dc.creatorEspinoza, L.spa
dc.date.accessioned2020-08-28T15:48:14Z
dc.date.available2020-08-28T15:48:14Z
dc.date.created1994-01-01spa
dc.description.abstractProlactin (PRL) is a neuroendocrine hormone that has important immunoregulatory properties. It is a potent mitogen in Nb2 T lymphoma cell line and stimulates both T-cell mediated and humoral immunity.' Recently an association between hyperprolactinaemia and certain rheumatic diseases has been described suggesting that PRL may play a role in the pathogenesis of some autoimmune diseases.94 In addition, PRL seems to be an autocrine factor required for viability and proliferation of B lymphoma cells.5 Furthermore, it was recently proposed that hyperprolactinaemia observed in oestrogentreated mice may predispose to development of lymphoma in these animals.6 Primary Sj6gren's syndrome (P-SS) is a chronic autoimmune disease characterised by exocrine glandular insufficiency secondary to lymphocytic and plasma cell infiltration. The spectrum of the disease extends from an organ specific autoimmune disease to a systemic involvement.7 Characteristically, patients with Sjogren's syndrome (SS) have an increased risk of developing lymphoma.'eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttp://dx.doi.org/10.1136/ard.53.6.425-a
dc.identifier.issnISSN: 0003-4967
dc.identifier.issnEISSN: 1468-2060
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/28453
dc.language.isoengspa
dc.publisherBMJ Publishing Groupspa
dc.relation.citationEndPage428
dc.relation.citationIssueNo. 53
dc.relation.citationStartPage425
dc.relation.citationTitleAnnals of the Rheumatic Diseases
dc.relation.ispartofAnnals of the Rheumatic Diseases, ISSN: 0003-4967; EISSN: 1468-2060, No.53 (June, 1994); pp. 425-428spa
dc.relation.urihttps://ard.bmj.com/content/53/6/425.1spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.sourceAnnals of the Rheumatic Diseasesspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordHyperprolactinaemiaspa
dc.subject.keywordPrimary Sjogren's syndromespa
dc.titleHyperprolactinaemia in primary Sjogren's syndrome [1]spa
dc.title.TranslatedTitleHiperprolactinemia en el síndrome de Sjogren primario [1]spa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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