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Physiological and pathological implications of laminins: From the gene to the protein

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dc.creatorPáez M.-C.spa
dc.creatorGonzález M.-J.spa
dc.creatorSerrano N.C.spa
dc.creatorShoenfeld Y.spa
dc.creatorAnaya, Juan-Manuelspa
dc.date.accessioned2020-05-26T00:01:49Z
dc.date.available2020-05-26T00:01:49Z
dc.date.created2007spa
dc.description.abstractThe extracellular matrix plays an important role in modulating the behavior of cells with which it interacts. There are a number of families of extracellular matrix (ECM) proteins including collagens, proteoglycans and laminins (LM). LM are the major component of the basal lamina (BL). Here, we review the current knowledge on their structure, self-assembly, binding mechanisms, diverse tissue-expression patterns and its impact on pathology. Studies and hypothesis exploring the role of LM and their polymorphic genes on autoimmune diseases (AIDs) such as systemic lupus erythematosus and Sjögren’s syndrome (SS) are also discussed. © 2018, Taylor and Francis Ltd. All rights reserved.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1080/08916930600911519
dc.identifier.issn8916934
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23411
dc.language.isoengspa
dc.publisherTaylor and Francis Ltdspa
dc.relation.citationEndPage94
dc.relation.citationIssueNo. 2
dc.relation.citationStartPage83
dc.relation.citationTitleAutoimmunity
dc.relation.citationVolumeVol. 40
dc.relation.ispartofAutoimmunity, ISSN:8916934, Vol.40, No.2 (2007); pp. 83-94spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-34250327154&doi=10.1080%2f08916930600911519&partnerID=40&md5=928e702e3ce0ddfb47455eefa3c68287spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordIntegrinspa
dc.subject.keywordtertiaryeng
dc.subject.keywordLamininspa
dc.subject.keywordgeneticeng
dc.subject.keywordsystemiceng
dc.subject.keywordLamininspa
dc.subject.keywordArticlespa
dc.subject.keywordAutoimmune diseasespa
dc.subject.keywordCentral nervous systemspa
dc.subject.keywordEmbryo developmentspa
dc.subject.keywordExtracellular matrixspa
dc.subject.keywordGene structurespa
dc.subject.keywordGenetic polymorphismspa
dc.subject.keywordGenetic regulationspa
dc.subject.keywordHemidesmosomespa
dc.subject.keywordHumanspa
dc.subject.keywordKidneyspa
dc.subject.keywordNeuromuscular systemspa
dc.subject.keywordNidationspa
dc.subject.keywordNonhumanspa
dc.subject.keywordPlacenta developmentspa
dc.subject.keywordPreimplantation embryospa
dc.subject.keywordPromoter regionspa
dc.subject.keywordProtein analysisspa
dc.subject.keywordProtein domainspa
dc.subject.keywordProtein structurespa
dc.subject.keywordSjoegren syndromespa
dc.subject.keywordSkinspa
dc.subject.keywordSystemic lupus erythematosusspa
dc.subject.keywordTissue distributionspa
dc.subject.keywordAntibody specificityspa
dc.subject.keywordAutoimmune diseasespa
dc.subject.keywordBasement membranespa
dc.subject.keywordChemistryspa
dc.subject.keywordGeneticsspa
dc.subject.keywordMetabolismspa
dc.subject.keywordPhysiologyspa
dc.subject.keywordProtein conformationspa
dc.subject.keywordProtein tertiary structurespa
dc.subject.keywordReviewspa
dc.subject.keywordSjoegren larsson syndromespa
dc.subject.keywordAutoimmune diseasesspa
dc.subject.keywordBasement membranespa
dc.subject.keywordHumansspa
dc.subject.keywordLamininspa
dc.subject.keywordLupus erythematosuseng
dc.subject.keywordOrgan specificityspa
dc.subject.keywordPolymorphismeng
dc.subject.keywordProtein conformationspa
dc.subject.keywordProtein structureeng
dc.subject.keywordSjogren-larsson syndromespa
dc.subject.keywordBasal laminaspa
dc.subject.keywordExtracellular matrixspa
dc.subject.keywordLamininspa
dc.subject.keywordSjögren’s syndromespa
dc.subject.keywordSystemic lupus erythematosusspa
dc.titlePhysiological and pathological implications of laminins: From the gene to the proteinspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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