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A functional variant in MIR137, a candidate gene for schizophrenia, affects Stroop test performance in young adults

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dc.creatorGonzález-Giraldo, Yeimyspa
dc.creatorGonzález Reyes, Rodrigo Estebanspa
dc.creatorGarzon-Forero, Diego Aspa
dc.date.accessioned2020-08-19T14:42:18Z
dc.date.available2020-08-19T14:42:18Z
dc.date.created2016-02-28spa
dc.description.abstractMIR137, a brain expressed miRNA, has been identified as a top novel susceptibility gene for schizophrenia (SZ). 230 healthy participants completed the Stroop test and were genotyped for a functional Variable Number Tandem Repeat (VNTR) in MIR137 gene. MIR137 VNTR genotypes were associated with differences in Stroop facilitation and accuracies in congruent trials and for the total number of errors. This is the first study of the functional VNTR in MIR137 gene and Stroop test performance in healthy subjects. Our results could have important implications for the identification of genetic candidates for endophenotypes for SZ.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.psychres.2016.01.006
dc.identifier.issnISSN: 0165-1781
dc.identifier.issnEISSN: 1872-7123
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/27464
dc.language.isoengspa
dc.publisherElsevierspa
dc.relation.citationEndPage205
dc.relation.citationStartPage202
dc.relation.citationTitlePsychiatry Research
dc.relation.citationVolumeVol. 236
dc.relation.ispartofPsychiatry Research, ISSN: 0165-1781;EISSN: 1872-7123, Vol.236 (2016); pp. 202-205 spa
dc.relation.urihttps://www.sciencedirect.com/science/article/abs/pii/S0165178115303498spa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourcePsychiatry Researchspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordExecutive functionspa
dc.subject.keywordEndophenotypesspa
dc.subject.keywordMicroRNAsspa
dc.titleA functional variant in MIR137, a candidate gene for schizophrenia, affects Stroop test performance in young adultsspa
dc.title.TranslatedTitleUna variante funcional en MIR137, un gen candidato para la esquizofrenia, afecta el rendimiento de la prueba de Stroop en adultos jóvenesspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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