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Changes in selenium levels in epilepsy

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dc.creatorGutiérrez-Álvarez A.M.spa
dc.creatorMoreno C.B.spa
dc.creatorGonzález Reyes, Rodrigo Estebanspa
dc.date.accessioned2020-05-25T23:59:54Z
dc.date.available2020-05-25T23:59:54Z
dc.date.created2005spa
dc.description.abstractIntroduction. It has been suggested that antiepileptic drug therapies deplete total body selenium stores and failure to give appropriate selenium supplementation, especially to patients receiving valproic acid during pregnancy may increase the risk of neural tube defects or other free radical mediated damage. Selenium is essential for the synthesis of selenoproteins, including glutathione peroxidase. Aims. To review the present state of knowledge about selenium behaviour in people with epilepsy taking antiepileptic drugs and to develop guidelines for the appropriate use of selenium supplements. Development. Databases such as Medline, Embase, Scisearch and Lilacs were consulted to have access to literature. A search in said databases was performed in order to find articles published from January 1966 to August 2004. All articles published in English and Spanish were considered. A manual review of the references present in each produced article was done in order to identify the articles that the electronic search may have not found itself. The title and abstract of the potential articles were analyzed before asking for the complete article. However, articles which seemed ambiguous were completely analyzed later to establish their relevance. Conclusions. There is insufficient evidence to fully evaluate the effect of selenium supplementation. The possible beneficial effects on pregnancy need to be evaluated in further studies. © 2005, Revista de Neurología.eng
dc.format.mimetypeapplication/pdf
dc.identifier.issn2100010
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/23128
dc.language.isoengspa
dc.relation.citationEndPage116
dc.relation.citationIssueNo. 2
dc.relation.citationStartPage111
dc.relation.citationTitleRevista de Neurologia
dc.relation.citationVolumeVol. 40
dc.relation.ispartofRevista de Neurologia, ISSN:2100010, Vol.40, No.2 (2005); pp. 111-116spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-24344471374&partnerID=40&md5=3204694ef4d385275d26f2d55e941541spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAnticonvulsive agentspa
dc.subject.keywordFree radicalspa
dc.subject.keywordGlutathione peroxidasespa
dc.subject.keywordSeleniumspa
dc.subject.keywordSelenoproteinspa
dc.subject.keywordValproic acidspa
dc.subject.keywordAnticonvulsive agentspa
dc.subject.keywordProteinspa
dc.subject.keywordSeleniumspa
dc.subject.keywordSelenoproteinspa
dc.subject.keywordBehaviorspa
dc.subject.keywordData basespa
dc.subject.keywordEpilepsyspa
dc.subject.keywordHumanspa
dc.subject.keywordMedical literaturespa
dc.subject.keywordMedical researchspa
dc.subject.keywordNeural tube defectspa
dc.subject.keywordPractice guidelinespa
dc.subject.keywordPregnancyspa
dc.subject.keywordProtein synthesisspa
dc.subject.keywordReviewspa
dc.subject.keywordVitamin supplementationspa
dc.subject.keywordBibliographic databasespa
dc.subject.keywordBloodspa
dc.subject.keywordDegenerative diseasespa
dc.subject.keywordDiet supplementationspa
dc.subject.keywordEpilepsyspa
dc.subject.keywordFemalespa
dc.subject.keywordMetabolismspa
dc.subject.keywordOxidative stressspa
dc.subject.keywordAnticonvulsantsspa
dc.subject.keywordDatabaseseng
dc.subject.keywordDietary supplementsspa
dc.subject.keywordEpilepsyspa
dc.subject.keywordFemalespa
dc.subject.keywordHumansspa
dc.subject.keywordNeurodegenerative diseasesspa
dc.subject.keywordOxidative stressspa
dc.subject.keywordPregnancyspa
dc.subject.keywordProteinsspa
dc.subject.keywordSeleniumspa
dc.subject.keywordSelenoproteinsspa
dc.subject.keywordAnticonvulsantsspa
dc.subject.keywordEpilepsyspa
dc.subject.keywordEvidence-based medicinespa
dc.subject.keywordSeleniumspa
dc.subject.keywordTrace elementsspa
dc.titleChanges in selenium levels in epilepsyspa
dc.title.TranslatedTitleAlteración de la concentración de selenio en la epilepsiaspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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