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Experiencia en el manejo de cancer colorrectal en el hospital universitario mayor - Mederi

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dc.contributor.advisorFigueroa Avendaño, Carlos Edgar
dc.creatorAgudelo Jimenez, Leidy
dc.creator.degreeEspecialista en Cirugía General
dc.date.accessioned2016-03-07T21:43:30Z
dc.date.available2016-03-07T21:43:30Z
dc.date.created2015-11-06
dc.date.issued2015
dc.descriptionIntroducción: El cáncer colorrectal es el tercer cáncer más diagnosticado en los hombres y el segundo en las mujeres a nivel mundial. Hasta 1.000 casos nuevos se diagnostican en Colombia cada año, por lo que es importante conocer la experiencia con esta patología en un centro de experiencia recientemente creado en el “Méderi, Hospital Universitario Mayor”. Materiales y métodos: Se realizó un estudio de corte transversal de la población con diagnóstico de cáncer colorrectal atendida entre agosto 2012 y diciembre 2014 que corresponde al tiempo de funcionamiento del servicio de Coloproctología. Resultados: Se atendieron un total de 152 pacientes con cáncer colorrectal en la institución. Se operó el 91% de los pacientes. El estadío más frecuente fue el IV. Solo el 4.9% presentó dehiscencia de anastomosis, datos concordantes con la literatura cuando el manejo es a cargo de expertos. El subtipo histológico más frecuente fue adenocarcinoma moderadamente diferenciado y la mortalidad perioperatoria de 2.63%. Discusión: El cáncer colorrectal es una entidad con alta morbimortalidad lo cual puede cambiar si se realizan pruebas de tamizaje, para realizar un manejo temprano y oportuno. Además juega un papel importante la experiencia del cirujano y la discusión de los pacientes en juntas multidisciplinarias. Palabras clave: cáncer de colon, cáncer de recto, epidemiología, estadificaciónspa
dc.description.abstractIntroduction: Colorectal cancer is the third most diagnosed cancer in men and second in women worldwide, up to 1,000 new cases are diagnosed each year in Colombia; due to its importance it is important to know the experience in a Experience Center recently created at the University Hospital Mayor Mederi . Methods: A cross-sectional study was conducted including all the population with a diagnosis of colorectal cancer who attended our institution in the period between August 2012 and December 2014, the period of creation of the Department of Coloproctology. Results: A total of 152 patients with colorectal cancer were treated in the institution, 91% of patients underwrnt a surgical treatment.. The most common postoperative stage was IV. Only 4.9% had anastomotic dehiscence, data consistent with literature in the management of this pathology in expert hands. The most common histological subtype was adenocarcinoma moderately differentiated, and perioperative mortality was 2.69%. . Discussion: Colorectal cancer is an entity with high morbidity and mortality which could change if screening tests are performed, to make and early and timely management. The surgeon´s experience and discussion of patients in multidisciplinary meetings also play an important role for them Keywords: colon cancer, rectal cancer, epidemiology, stagingeng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.48713/10336_11811
dc.identifier.urihttp://repository.urosario.edu.co/handle/10336/11811
dc.language.isospa
dc.publisherUniversidad del Rosariospa
dc.publisher.departmentFacultad de Medicinaspa
dc.publisher.programEspecialización en Cirugía Generalspa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
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dc.rights.ccAtribución-NoComercial-SinDerivadas 2.5 Colombiaspa
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dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
dc.source.bibliographicCitationJemal A, Bray F, Ferlay J. Global Cancer Statistics. 2012;61(2):69–90
dc.source.bibliographicCitationSiegel R, Naishadham D, Jemal A. Cancer statistics for Hispanics/Latinos, 2012. CA Cancer J Clin [Internet]. 2012 [cited 2015 Feb 17];62(5):283–98. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22987332
dc.source.bibliographicCitationDeSantis CE, Lin CC, Mariotto AB, Siegel RL, Stein KD, Kramer JL, et al. Cancer treatment and survivorship statistics, 2014. CA Cancer J Clin [Internet]. 2014 Jun 1 [cited 2014 Jul 9]; Available from: http://www.ncbi.nlm.nih.gov/pubmed/24890451
dc.source.bibliographicCitationGarcía-Alvarez A, Serra-Majem L, Ribas-Barba L, Castell C, Foz M, Uauy R, et al. Obesity and overweight trends in Catalonia, Spain (1992-2003): gender and socio-economic determinants. Public Health Nutr [Internet]. 2007 Nov [cited 2015 Jan 6];10(11A):1368–78. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17988408
dc.source.bibliographicCitationGrupo de vigilancia epidemiológica. Instituto nacional de cancerología. 2002-2006
dc.source.bibliographicCitationCir RC, Original C. Características clínicas , demográficas e histopatológicas de los pacientes con cáncer colorrectal del Hospital Universitario de Santander. 2012;213–20.
dc.source.bibliographicCitationConteduca V, Sansonno D, Russi S, Dammacco F. Precancerous colorectal lesions (Review). Int J Oncol [Internet]. 2013 Oct [cited 2015 Jan 6];43(4):973–84. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23900573
dc.source.bibliographicCitationMatsuda T, Kawano H, Hisabe T, Ikematsu H, Kobayashi N, Mizuno K, et al. Current status and future perspectives of endoscopic diagnosis and treatment of diminutive colorectal polyps. Dig Endosc [Internet]. 2014 Apr [cited 2015 Jan 7];26 Suppl 2:104–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24750158
dc.source.bibliographicCitationNaini B V, Odze RD. Advanced precancerous lesions (APL) in the colonic mucosa. Best Pract Res Clin Gastroenterol [Internet]. Elsevier Ltd; 2013 Apr [cited 2015 Jan 7];27(2):235–56. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23809243
dc.source.bibliographicCitationAihara H, Kumar N, Thompson CC. Diagnosis, surveillance, and treatment strategies for familial adenomatous polyposis: rationale and update. Eur J Gastroenterol Hepatol [Internet]. 2014 Mar [cited 2015 Jan 6];26(3):255–62. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24161962
dc.source.bibliographicCitationPatel SG, Ahnen DJ. Familial colon cancer syndromes: an update of a rapidly evolving field. Curr Gastroenterol Rep [Internet]. 2012 Oct [cited 2014 Dec 31];14(5):428–38. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3448005&tool=pmcentrez&rendertype=abstract
dc.source.bibliographicCitationKopacova M. Peutz-Jeghers syndrome: Diagnostic and therapeutic approach. World J Gastroenterol [Internet]. 2009 [cited 2015 Jan 7];15(43):5397. Available from: http://www.wjgnet.com/1007-9327/15/5397.asp
dc.source.bibliographicCitationTomlinson IPM. Syndrome of the month Peutz-Jeghers syndrome. 1997;1007–11
dc.source.bibliographicCitationRustgi AK. The genetics of hereditary colon cancer. 2007;2525–38.
dc.source.bibliographicCitationOmundsen M, Lam FF. The other colonic polyposis syndromes. ANZ J Surg [Internet]. 2012 Oct [cited 2015 Jan 8];82(10):675–81. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22906058
dc.source.bibliographicCitationChow E, Macrae F. A review of juvenile polyposis syndrome. J Gastroenterol Hepatol [Internet]. 2005 Nov [cited 2015 Jan 8];20(11):1634–40. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16246179
dc.source.bibliographicCitationBronner MP. Gastrointestinal polyposis syndromes. Am J Med Genet A [Internet]. 2003 Nov 1 [cited 2015 Jan 8];122A(4):335–41. Available from: http://www.ncbi.nlm.nih.gov/pubmed/14518072
dc.source.bibliographicCitationSteinke V, Engel C, Büttner R, Schackert HK, Schmiegel WH, Propping P. Hereditary nonpolyposis colorectal cancer (HNPCC)/Lynch syndrome. Dtsch Arztebl Int [Internet]. 2013 Jan [cited 2015 Jan 10];110(3):32–8. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3566622&tool=pmcentrez&rendertype=abstract
dc.source.bibliographicCitationBarrow E, Hill J, Evans DG. Cancer risk in Lynch Syndrome. 2013;229–40
dc.source.bibliographicCitationBeaugerie L, Svrcek M, Seksik P, Bouvier A-M, Simon T, Allez M, et al. Risk of colorectal high-grade dysplasia and cancer in a prospective observational cohort of patients with inflammatory bowel disease. Gastroenterology [Internet]. Elsevier, Inc; 2013 Jul [cited 2015 Jan 6];145(1):166–75.e8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23541909
dc.source.bibliographicCitationHamilton W, Round a, Sharp D, Peters TJ. Clinical features of colorectal cancer before diagnosis: a population-based case-control study. Br J Cancer [Internet]. 2005 Aug 22 [cited 2015 Jan 9];93(4):399–405. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2361578&tool=pmcentrez&rendertype=abstract
dc.source.bibliographicCitationMajumdar SR, Fletcher RH, Sc MDM, D ATEM. How Does Colorectal Cancer Present ? Symptoms , Duration , and Clues to Location. 1999;
dc.source.bibliographicCitationVan De Velde CJH, Boelens PG, Borras JM, Coebergh JW, Cervantes A, Blomqvist L, et al. EURECCA colorectal: Multidisciplinary management: European consensus conference colon & rectum. Eur J Cancer. 2014;50(1).
dc.source.bibliographicCitationLaubert T, Habermann JK, Bader FG, Jungbluth T, Esnaashari H, Bruch H-P, et al. Epidemiology, molecular changes, histopathology and diagnosis of colorectal cancer. Eur Surg [Internet]. 2010 Dec [cited 2015 Jan 20];42(6):252–9. Available from: http://link.springer.com/10.1007/s10353-010-0581-7
dc.source.bibliographicCitationTurgeon DK, Ruffin MT. Screening strategies for colorectal cancer in asymptomatic adults. Prim Care [Internet]. Elsevier Inc; 2014 Jun [cited 2015 Mar 19];41(2):331–53. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24830611
dc.source.bibliographicCitationOutcomes TC, Therapy S, Group S. A comparison of laparoscopically assisted and open colectomy for colon cancer. N Engl J Med. 2004;350(20):2050–9.
dc.source.bibliographicCitationFleshman J, Sargent DJ, Green E, Anvari M, Stryker SJ, Beart RW, et al. Laparoscopic colectomy for cancer is not inferior to open surgery based on 5-year data from the COST Study Group trial. Ann Surg. 2007;246(4):655–62; discussion 662–4.
dc.source.bibliographicCitationFujihara S, Mori H, Kobara H, Nishiyama N, Matsunaga T, Ayaki M, et al. Current innovations in endoscopic therapy for the management of colorectal cancer: From endoscopic submucosal dissection to endoscopic full-thickness resection. Biomed Res Int. 2014;2014.
dc.source.bibliographicCitationHompes R, Cunningham C. Colorectal cancer: Management. Medicine (Baltimore) [Internet]. Elsevier Ltd; 2011;39(5):254–8. Available from: http://dx.doi.org/10.1016/j.mpmed.2011.02.002
dc.source.bibliographicCitationHatcher O, Kumar A a. Chemotherapy and radiotherapy for colorectal cancers. Surg [Internet]. Elsevier Ltd; 2014;32(4):179–84. Available from: http://www.sciencedirect.com/science/article/pii/S0263931914000180
dc.source.bibliographicCitationFolkesson J, Birgisson H, Pahlman L, Cedermark B, Glimelius B, Gunnarsson U. Swedish rectal cancer trial: Long lasting benefits from radiotherapy on survival and local recurrence rate. J Clin Oncol. 2005;23(24):5644–50.
dc.source.bibliographicCitationLoehrer PJ. Chemotherapy with Preoperative Radiotherapy in Rectal Cancer. Yearb Oncol. 2008;2008:229–31.
dc.source.bibliographicCitationSiegel RL, Miller KD, Jemal A. Cancer Statistics, 2015. CA Cancer J Clin. 2015;65(1):5–29.
dc.source.bibliographicCitationGiessen C, Laubender RP, Ankerst DP, Stintzing S, Modest DP, Mansmann U, et al. Progression-free survival as a surrogate endpoint for median overall survival in metastatic colorectal cancer: Literature-based analysis from 50 randomized first-line trials. Clin Cancer Res. 2013;19(1):225–35.
dc.source.bibliographicCitationKopetz S, Chang GJ, Overman MJ, Eng C, Sargent DJ, Larson DW, et al. Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy. J Clin Oncol. 2009;27(22):3677–83.
dc.source.bibliographicCitationBowne WB. Stents for Palliation of Obstructive Metastatic Colon Cancer—Invited Critique. Arch Surg. 2007;142(7):623.
dc.source.bibliographicCitationWasserberg N, Kaufman HS. Palliation of colorectal cancer. Surg Oncol. 2007;16(4):299–310.
dc.source.bibliographicCitationCavalli-Björkman N, Lambe M, Eaker S, Sandin F, Glimelius B. Differences according to educational level in the management and survival of colorectal cancer in Sweden. Eur J Cancer. 2011;47(9):1398–406.
dc.source.bibliographicCitationVan Gijn W, Gooiker G a., Wouters MWJM, Post PN, Tollenaar R a EM, Van De Velde CJH. Volume and outcome in colorectal cancer surgery. Eur J Surg Oncol [Internet]. Elsevier Ltd; 2010;36(SUPPL. 1):S55–63. Available from: http://dx.doi.org/10.1016/j.ejso.2010.06.027
dc.source.bibliographicCitationRim SH, Seeff L, Ahmed F, King JB, Coughlin SS. Colorectal cancer incidence in the United States, 1999-2004 : an updated analysis of data from the National Program of Cancer Registries and the Surveillance, Epidemiology, and End Results Program. Cancer. 2009;115(9):1967–76.
dc.source.bibliographicCitationShivaram K, James E. Colorectal cancer: prevention and early diagnosis.
dc.source.bibliographicCitationDaudt HML, Cosby C, Dennis DL, Payeur N, Nurullah R. Nutritional and psychosocial status of colorectal cancer patients referred to an outpatient oncology clinic. Support Care Cancer [Internet]. 2012;20(7):1417–23. Available from: http://link.springer.com/10.1007/s00520-011-1224-7
dc.source.bibliographicCitationSchneider NI, Langner C. Prognostic stratification of colorectal cancer patients: Current perspectives. Cancer Manag Res [Internet]. 2014;6(1):291–300. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=4085313&tool=pmcentrez&rendertype=abstract
dc.source.bibliographicCitationKingham TP, Pachter HL. Colonic Anastomotic Leak: Risk Factors, Diagnosis, and Treatment. J Am Coll Surg [Internet]. American College of Surgeons; 2009;208(2):269–78. Available from: http://linkinghub.elsevier.com/retrieve/pii/S1072751508015299
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subjectcáncer de rectospa
dc.subjectCáncer de rectospa
dc.subjectCáncer de colonspa
dc.subjectepidemiologíaspa
dc.subjectEpidemiologíaspa
dc.subjectcáncer de colonspa
dc.subjectestadificaciónspa
dc.subjectEstadificaciónspa
dc.subject.ddcVarias ramas de la medicina, Cirugía
dc.subject.decsCirugía colorrectalspa
dc.subject.decsNeoplasias colorrectalesspa
dc.subject.keywordcolon cancereng
dc.subject.keywordrectal cancereng
dc.subject.keywordepidemiologyeng
dc.subject.keywordstagingeng
dc.subject.lembCirugíaspa
dc.titleExperiencia en el manejo de cancer colorrectal en el hospital universitario mayor - Mederispa
dc.typemasterThesiseng
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersion
dc.type.spaTrabajo de gradospa
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Especialización en Cirugía General