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The autoimmune tautology with a focus on antiphospholipid syndrome
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Autores
Franco, J-S
Anaya, Juan-Manuel
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2014
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SAGE Publications Ltd
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Abstract
Autoimmune diseases (ADs) are often diagnosed according to classification criteria; however, they share similar subphenotypes including signs and symptoms, non-specific autoantibodies and other immune changes, which are prone to taxonomic problems. Polyautoimmunity is defined as the presence of more than one AD in a single patient. The close relationship between antiphospholipid syndrome (APS) and systemic lupus erythematosus has been studied throughout the years. However, APS may coexist with several other ADs confirming polyautoimmunity in this systemic disease. Herein, we summarized the common characteristics shared between APS and others ADs in light of the autoimmune tautology (that is, common mechanisms of autoimmune diseases). © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.
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Keywords
Autoantibody , systemic , Antiphospholipid syndrome , Autoimmune disease , Conference paper , Disease classification , Human , Physical disease by body function , Systemic disease , Systemic lupus erythematosus , Antiphospholipid syndrome , Autoimmunity , Complication , Immunology , Antiphospholipid syndrome , Autoimmunity , Humans , Lupus erythematosus , Antiphospholipid syndrome , Autoimmune diseases , Cardiovascular disease , Autoimmune tautology , Polyautoimmunity
