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Gynaecological cancer and night shift work: A systematic review

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Schwarz C.
Pedraza Flechas, Ana María
Lope V.
Pastor-Barriuso R.
Pollan M.
Perez-Gomez B.

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2018

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Elsevier Ireland Ltd

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Abstract
Night shift work can affect hormonal balance, and so might be a risk factor for gynaecological malignancies. This report presents a systematic review on the association between this occupational exposure and the incidence of gynaecological cancers other than breast cancer. We searched for original articles addressing this issue in PubMed/MEDLINE, EMBASE and Web of Science, and used the Newcastle–Ottawa Quality Index to evaluate the methodological quality of those reports selected for review. Globally, we found only six articles, which provided the results of just six research studies: four examined ovarian cancer, two endometrial tumours and two cervical cancer. Our results show that this matter has received scant attention from the research community, and that the little evidence available does not show any clear relationship between night shift work and ovarian, endometrial or cervical cancer. More prospective rigorous studies are needed to evaluate these associations. © 2018 Elsevier B.V.
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Keywords
Case control study , Embase , Endometrium cancer , Female , Follow up , Human , Medline , Newcastle-ottawa scale , Night shift , Observational study , Ovary cancer , Review , Systematic review , Uterine cervix cancer , Web of science , Female genital tract tumor , Shift schedule , Female , Genital neoplasms, female , Humans , Shift work schedule , Cervical cancer , Endometrial cancer , Nightshift work , Ovarian cancer , Systematic review
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