Ítem
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Bilateral Iris Depigmentation and Ocular Hypotony as End-Stage Manifestations of Untreated Vogt–Koyanagi–Harada Disease
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Autores
Cuevas M.
de-la-Torre, Alejandra
Córdoba A.
Fecha
2018
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Taylor and Francis Ltd
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Resumen
Abstract
Purpose: To describe severe bilateral iris depigmentation and persistent ocular hypotony as end-stage manifestations of untreated Vogt–Koyanagi–Harada disease. Methods: We present the clinical findings and diagnostic studies performed for three patients with bilateral iris depigmentation. Results: Vogt–Koyanagi–Harada disease in late recurrent stage was diagnosed in three patients with bilateral severe iris depigmentation and persistent ocular hypotony. Conclusions: Early diagnosis and treatment of inflammation are crucial factors in the clinical outcome of Vogt–Koyanagi–Harada disease. When left undiagnosed and untreated from early stages, severe iris depigmentation and ocular hypotony, uncommon manifestations of this disease, can develop. ©, © Taylor and Francis Group, LLC.
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Keywords
Cyclosporine , Dexamethasone , optical coherence , Folic acid , Methotrexate , Prednisone , Adult , Aged , Anterior eye chamber , Antiangiogenic activity , Arm , Article , B scan , Best corrected visual acuity , Bilateral iris depigmentation , Biomicroscopy , Case report , Cataract , Cataract extraction , Ciliary body , Clinical article , Clinical feature , Clinical outcome , Consultation , Cornea , Depigmentation , Diagnostic test , Disease duration , Disease severity , Drug dose escalation , Early diagnosis , Eye examination , Eye fundus , Eyelid , Female , Granulomatosis , Hand , Health service , Hospital admission , Human , Immunosuppressive treatment , Intraocular hypertension , Intraocular hypotension , Intraocular pressure , Iris atrophy , Iris disease , Lens implantation , Macular edema , Male , Medical history , Middle aged , Multiple cycle treatment , Neck , Optical coherence tomography , Patient referral , Pterygium , Recurrent disease , Retina detachment , Retina fluorescein angiography , Retina macula cystoid edema , Slit lamp microscopy , Transillumination , Treatment indication , Uveitis , Visual acuity , Vitiligo , Vitrectomy , Vitreous opacity , Vogt koyanagi syndrome , Atrophy , Hypopigmentation , Intraocular hypotension , Iris , Iris disease , Meningoencephalitis , Pathology , Pigment epithelium , Slit lamp , Adult , Aged , Atrophy , Female , Humans , Hypopigmentation , Iris , Iris diseases , Male , Middle aged , Ocular hypotension , Pigment epithelium of eye , Slit lamp , Tomography , Uveomeningoencephalitic syndrome , Iris atrophy , Iris depigmentation , Ocular hypotony , Panuveitis , Vkh , Vogt–koyanagi–harada disease
