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Long-term effect of intravitreal triamcinolone in the nonproliferative stage of type II idiopathic parafoveal telangiectasia

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WU, LIHTEH
EVANS, TEODORO
ARÉVALO, J FERNANDO
BERROCAL, MARÍA H.
RODRÍGUEZ, FRANCISCO J.
HSU, MARÍA
SÁNCHEZ, JUAN G.

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2008

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Abstract
PURPOSE: To report the visual outcomes and ocular complications of intravitreal triamcinolone acetonide (IVTA) in the treatment of the nonproliferative stage of type II idiopathic parafoveal telangiectasia (IPT). METHODS: Retrospective, multicenter, uncontrolled interventional case series of 19 eyes of 14 consecutive patients with the nonproliferative stage of IPT that had undergone at least one intravitreal injection of 4 mg of triamcinolone acetonide. Demographic, medical, and ocular data were obtained through chart review. The main outcome measures included best-corrected visual acuity at several timepoints of follow up and ocular complications. RESULTS: At baseline the mean logMAR visual acuity was 0.83 ± 0.41 (Snellen 20/135, range 0.3-2). After an average follow-up of 21.2 months (range 6-44 months), the mean logMAR visual acuity remained essentially unchanged from baseline. At 3 months, the logMAR visual acuity was 0.86 ± 0.44 (Snellen 20/145, P = 0.8378), at 6 months 0.86 ± 0.42 (Snellen 20/145, P = 0.8149), at 12 months 0.87 ± 0.46 (Snellen 20/148, P > 0.9999), at 18 months 0.84 ± 0.35 (Snellen 20/138, P = 0.8385), and at the last follow-up 0.82 ± 0.44 (Snellen 20/132, P = 0.9301). Seven eyes were reinjected once. Ten of 19 eyes (53%) developed cataract (3 eyes underwent phacoemulsification and intraocular lens implantation) and 7 of 19 eyes (37%) had an elevated intraocular pressure, none of which required surgical treatment. CONCLUSION: IVTA does not seem to improve visual acuity in most eyes with the nonproliferative stage of IPT. © The Ophthalmic Communications Society, Inc.
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Triamcinolone , Glucocorticoid , Triamcinolone acetonide , Adult , Aged , Article , Cataract , Cataract extraction , Clinical article , Controlled study , Disease severity , Drug effect , Female , Follow up , Human , Intraocular pressure , Lens implant , Male , Phacoemulsification , Telangiectasia , Treatment outcome , Type 2 idiopathic parafoveal telangiectasia , Visual acuity , Clinical trial , Fluorescence angiography , Injection , Middle aged , Multicenter study , Pathology , Retina blood vessel , Retina disease , Retina fovea , Retrospective study , Telangiectasia , Vitreous body , Aged , Female , Fluorescein angiography , Fovea centralis , Glucocorticoids , Humans , Injections , Male , Middle aged , Retinal diseases , Retinal vessels , Retrospective studies , Telangiectasis , Treatment outcome , Triamcinolone acetonide , Visual acuity , Vitreous body , Juxtafoveolar telangiectasis , Macular edema , Macular telangiectasia , Parafoveal telangiectasis , Perifoveal telangiectasia , Triamcinolone
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