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Candida albicans resistence mechanisms, tools for its analysis

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Autores
Pinilla Bermúdez G.
Muñoz Henao, Julián Esteban
Navarrete Ospina J.
Muñoz Molina L.C.
Lindarte Celis D.A.
Molano Aponte J.A.
Montes Castillo J.M.

Fecha
2018

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Comunicaciones Cientificas Mexicanas S.A. de C.V.

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Abstract
Candida albicans is a commensal yeast of the human microbiota, but that in immunosuppressed patients can cause localized and systemic infections. It has the ability to form a biofilm, through the production of extracellular polysaccharides that allow it to adhere to virtually any type of surface, live in communities and evade the action of the immune system. This capacity increases its resistance to antimicrobial molecules compared to microorganisms in free or planktonic state. Fluconazole and amphotericin b are the main drugs used against the infection caused by this microorganism; however, resistance to these antifungals and other azoles is a growing problem. In this review, proteomics is highlighted as an alternative tool for the analysis of C. albicans resistance mechanisms. © 2018 Comunicaciones Cientificas Mexicanas S.A. de C.V.. All rights reserved.
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Keywords
Antifungal resistance , Article , Candida albicans , Nonhuman , Proteomics , Candida albicans , Proteomics , Resistance mechanisms
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