Pregnancy failure and alkaline phosphatases: from mouse genetics to human disease.
Date
2012Share
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Abstract
In mammals, fertility is governed by a considerable number of genes, as materialized by the decreased or impaired fertility of ~20% of knock-out mice. We wished to study fertility parameters as quantitative genetic characters (QTL), using a very original model of interspecific recombinant congenic mice developed at the Pasteur Institute.
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