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Systemic lupus erythematosus in males: a study of 107 Latin American patients

Título de la revista
Autores
Molina, J F
Drenkard, C
Molina, J
Cardiel, M H
Uribe, O
Anaya, Juan-Manuel
Gomez, L J
Felipe, O
Ramirez, L A
Alarcon-Segovia, D

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Fecha
1996-05

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Williams & Wilkins
Wolters Kluwer Health

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Resumen
Abstract
Clinical and laboratory features were analyzed in 107 Latin American male patients with systemic lupus erythematosus (SLE) who were compared with a group of 1,209 Latin American female patients with SLE to determine the presence of gender-associated differences. Males had an increased prevalence of renal disease, vascular thrombosis, and the presence of anti-dsDNA antibodies, as well as the use of moderate to high doses of corticosteroids, compared with female SLE patients. Although there was no difference in mortality from all causes, SLE-related mortality was higher in the male group. All these findings are consistent with a more severe disease in Latin American males than in female patients from the same region.
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Keywords
Adolescent , Adult , Cause of Death , Lupus Erythematosus systemic complications
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