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Human immunoglobulin versus plasmapheresis in guillain-barre syndrome and myasthenia gravis: A meta-analysis

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dc.creatorOrtiz-Salas, Paolaspa
dc.creatorVelez-van-Meerbeke, Albertospa
dc.creatorGalvis-Gomez, Camilo Albertospa
dc.creatorQ, Jesús H. Rodriguezspa
dc.date.accessioned2020-05-25T23:56:03Z
dc.date.available2020-05-25T23:56:03Z
dc.date.created2016spa
dc.description.abstractObjectives: To evaluate the efficacy and safety over a short time period of human intravenous immunoglobulin versus plasma exchange (PE) in the management of some autoimmune neurologic diseases. In addition, length of hospital stay and duration of ventilator support were compared. Methods: Randomized controlled trials and analytical observational studies of more than 10 cases were reviewed. Cochrane Neuromuscular Disease Group trials, MEDLINE, EMBASE, HINARI, and Ovid, were searched as data source. Reference lists were examined for further relevant articles. A random-effect model was used to derive a pooled risk ratio. Results: A total of 552 articles were found and 24 met the criteria for a studied population of 4657 cases: 14 articles were about Guillain-Barré syndrome and 10 of myasthenia gravis. No evidence was found to suggest that PE or intravenous immunoglobulin differed in terms of efficacy or safety to treat any of the 2 diseases. Hospital stay length and ventilatory support time are different in each illness; however, we found no statistical difference in either of the 2 treatments. Conclusions: There is no evidence for superiority in the efficacy or safety of immunoglobulin or plasmapheresis in the management of Guillain-Barré syndrome and myasthenia gravis. However, caution should be exercised in the interpretation of these results given the limitations in the quality of the evidence and the heterogeneity of the studies. © 2016 Wolters Kluwer Health, Inc. All rights reserved.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1097/CND.0000000000000119
dc.identifier.issn15220443
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/22304
dc.language.isoengspa
dc.publisherLippincott Williams and Wilkinsspa
dc.relation.citationEndPage11
dc.relation.citationIssueNo. 1
dc.relation.citationStartPage1
dc.relation.citationTitleJournal of Clinical Neuromuscular Disease
dc.relation.citationVolumeVol. 18
dc.relation.ispartofJournal of Clinical Neuromuscular Disease, ISSN:15220443, Vol.18, No.1 (2016); pp. 1-11spa
dc.relation.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84983766452&doi=10.1097%2fCND.0000000000000119&partnerID=40&md5=147e1287e83f2e726a20d1b5ecfb7670spa
dc.rights.accesRightsinfo:eu-repo/semantics/openAccess
dc.rights.accesoAbierto (Texto Completo)spa
dc.source.instnameinstname:Universidad del Rosariospa
dc.source.reponamereponame:Repositorio Institucional EdocURspa
dc.subject.keywordAlbuminspa
dc.subject.keywordintravenouseng
dc.subject.keywordHuman immunoglobulinspa
dc.subject.keywordImmunoglobulinspa
dc.subject.keywordAcute kidney failurespa
dc.subject.keywordAllergic reactionspa
dc.subject.keywordAnemiaspa
dc.subject.keywordArticlespa
dc.subject.keywordArtificial ventilationspa
dc.subject.keywordBody weightspa
dc.subject.keywordChillspa
dc.subject.keywordDiarrheaspa
dc.subject.keywordDisabilityspa
dc.subject.keywordDrug efficacyspa
dc.subject.keywordDrug safetyspa
dc.subject.keywordDyspneaspa
dc.subject.keywordFaintnessspa
dc.subject.keywordFeverspa
dc.subject.keywordGuillain barre syndromespa
dc.subject.keywordHeadachespa
dc.subject.keywordHeart arrhythmiaspa
dc.subject.keywordHematomaspa
dc.subject.keywordHematuriaspa
dc.subject.keywordHemolytic anemiaspa
dc.subject.keywordHumanspa
dc.subject.keywordHypertensionspa
dc.subject.keywordHypertransaminasemiaspa
dc.subject.keywordHypocalcemiaspa
dc.subject.keywordHypotensionspa
dc.subject.keywordLength of stayspa
dc.subject.keywordMeningismspa
dc.subject.keywordMeta analysisspa
dc.subject.keywordMuscle weaknessspa
dc.subject.keywordMyasthenia gravisspa
dc.subject.keywordNausea and vomitingspa
dc.subject.keywordPhlebitisspa
dc.subject.keywordPlasmapheresisspa
dc.subject.keywordPneumoniaspa
dc.subject.keywordPriority journalspa
dc.subject.keywordRandomized controlled trial (topic)spa
dc.subject.keywordRashspa
dc.subject.keywordSensitivity analysisspa
dc.subject.keywordSepsisspa
dc.subject.keywordSystematic reviewspa
dc.subject.keywordTreatment outcomespa
dc.subject.keywordVasospasmspa
dc.subject.keywordVein thrombosisspa
dc.subject.keywordVertigospa
dc.subject.keywordComparative studyspa
dc.subject.keywordGuillain-barre syndromespa
dc.subject.keywordMyasthenia gravisspa
dc.subject.keywordPlasmapheresisspa
dc.subject.keywordProceduresspa
dc.subject.keywordGuillain-barre syndromespa
dc.subject.keywordHumansspa
dc.subject.keywordImmunoglobulinseng
dc.subject.keywordMyasthenia gravisspa
dc.subject.keywordPlasmapheresisspa
dc.subject.keywordRandomized controlled trials as topicspa
dc.subject.keywordTreatment outcomespa
dc.subject.keywordAdverse effectsspa
dc.subject.keywordAutoimmune neurologic diseasesspa
dc.subject.keywordEfficacyspa
dc.subject.keywordImmunoglobulinspa
dc.subject.keywordPlasma exchangespa
dc.titleHuman immunoglobulin versus plasmapheresis in guillain-barre syndrome and myasthenia gravis: A meta-analysisspa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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