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Cloning, expression, and characterisation of a Plasmodium vivax MSP7 family merozoite surface protein

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dc.creatorMongui, Alvarospa
dc.creatorPerez-Leal, Oscarspa
dc.creatorSoto, Sara C.spa
dc.creatorCortes, Jimenaspa
dc.creatorPatarroyo, Manuel A.spa
dc.date.accessioned2020-08-06T16:20:16Z
dc.date.available2020-08-06T16:20:16Z
dc.date.created2006-12-22spa
dc.description.abstractPlasmodium vivax remains the most widespread Plasmodium parasite specie around the world, producing about 75 million malaria cases, mainly in South America and Asia. A vaccine against this disease is of urgent need, making the identification of new antigens involved in target cell invasion, and thus potential vaccine candidates, a priority. A protein belonging to the P. vivax merozoite surface protein 7 (PvMSP7) family was identified in this study. This protein (named PvMSP71) has 311 amino acids displaying an N-terminal region sharing high identity with P. falciparum MSP7, as well as a similar proteolytical cleavage pattern. This protein’s expression in P. vivax asexual blood stages was revealed by immuno-histochemical and molecular techniques.eng
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.1016/j.bbrc.2006.10.082
dc.identifier.issnISSN: 0006-291X
dc.identifier.issnEISSN: 1090-2104
dc.identifier.urihttps://repository.urosario.edu.co/handle/10336/25940
dc.language.isoengspa
dc.publisherElsevierspa
dc.relation.citationEndPage644
dc.relation.citationIssueNo. 3
dc.relation.citationStartPage639
dc.relation.citationTitleBiochemical and Biophysical Research Communications
dc.relation.citationVolumeVol. 351
dc.relation.ispartofBiochemical and Biophysical Research Communications, ISSN: 0006-291X;EISSN: 1090-2104, Vol.351, No.3 (2006); pp.639-644spa
dc.relation.urihttps://www.sciencedirect.com/science/article/abs/pii/S0006291X0602328Xspa
dc.rights.accesRightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.accesoRestringido (Acceso a grupos específicos)spa
dc.sourceBiochemical and Biophysical Research Communicationsspa
dc.source.instnameinstname:Universidad del Rosario
dc.source.reponamereponame:Repositorio Institucional EdocUR
dc.subject.keywordMalariaspa
dc.subject.keywordPlasmodium vivaxspa
dc.subject.keywordMerozoitespa
dc.subject.keywordMSP7spa
dc.subject.keywordVaccine candidatespa
dc.titleCloning, expression, and characterisation of a Plasmodium vivax MSP7 family merozoite surface proteinspa
dc.title.TranslatedTitleClonación, expresión y caracterización de una proteína de superficie de merozoito de la familia Plasmodium vivax MSP7spa
dc.typearticleeng
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersion
dc.type.spaArtículospa
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