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Nerve conduction patterns in Guillain-Barré syndrome associated with zika virus infection in Cucuta, Colombia
| dc.contributor.advisor | Anaya, Juan-Manuel | |
| dc.contributor.advisor | Molano González, Nicolás | |
| dc.creator | González-Bravo, Diana | |
| dc.creator | Uncini, Antonino | |
| dc.creator | Ojeda, Ernesto C. | |
| dc.creator | Rodríguez Velandia, Yhojan Alexis | |
| dc.creator | Monsalve Carmona, Diana Marcela | |
| dc.creator | Vega, Daniel | |
| dc.creator | Paipilla, Deyanira | |
| dc.creator | Torres, Leidy | |
| dc.creator | Osorio, Jorge E. | |
| dc.creator | Anaya, Juan-Manuel | |
| dc.creator | Acosta Ampudia, Yeny Yasbleidy | |
| dc.creator | Ramírez Santana, Heily Carolina | |
| dc.creator | Molano González, Nicolás | |
| dc.creator.degree | Especialista en Epidemiología (en Convenio con el CES) | |
| dc.date.accessioned | 2018-04-18T20:10:26Z | |
| dc.date.available | 2018-04-18T20:10:26Z | |
| dc.date.created | 2018-04-10 | |
| dc.date.issued | 2018 | |
| dc.description.abstract | Background: Zika virus (ZIKV) infection has been associated with an increased incidence of Guillain-Barré syndrome (GBS) but the relative frequency of acute inflammatory demyelinating polyradiculoneuropathy (AIDP) and axonal GBS subtypes is controversial. Methods: Twenty-three GBS patients diagnosed according to Brighton criteria during the ZIKV outbreak in Cúcuta, Colombia, were evaluated clinically and electrophysiologically. Electrodiagnosis of GBS subtypes was made according to a recently described criteria set that proved to have a high diagnostic accuracy on the basis of a single test. The electrophysiological features of 34 Italian AIDP patients were used as control. Results: All patients had symptoms compatible with ZIKV infection before the onset of the GBS and the diagnosis of ZIKV infection was confirmed in 69.5 % of patients. Median time from onset of ZIKV infection symptoms to onset of GBS was 6 days (interquartile range, 6-14 days). Cranial nerve palsy was present in 82.6% of patients, facial palsy in 65.2%, autonomic dysfunction in 69.5%, and 43.4% of patients required mechanical ventilation. AIDP was diagnosed in 73.9% of patients. About 50% of nerves of the AIDP patients showed a prevalent demyelinating distal involvement but this pattern was not different from Italian AIDP patients without ZIKV infection. Conclusions: GBS associated with ZIKV infection is clinically characterized by a high frequency of cranial nerve involvement, autonomic dysfunction and necessity of mechanical ventilation indicating an aggressive and severe course. AIDP is the most frequent electrophysiological subtype. Demyelination is prevalently distal but this pattern is not specific of ZIKV infection. | eng |
| dc.description.embargo | 2019-08-01 06:01:01: Script de automatizacion de embargos. info:eu-repo/date/embargoEnd/2019-04-18 | spa |
| dc.description.sponsorship | Centro de Estudio de Enfermedades Autoinmunes- CREA | spa |
| dc.description.sponsorship | Universidad del Rosario | spa |
| dc.format.mimetype | application/pdf | |
| dc.identifier.doi | https://doi.org/10.48713/10336_17917 | |
| dc.identifier.uri | http://repository.urosario.edu.co/handle/10336/17917 | |
| dc.language.iso | spa | |
| dc.publisher | Universidad del Rosario | spa |
| dc.publisher.department | Facultad de medicina | spa |
| dc.rights | Atribución-NoComercial-SinDerivadas 2.5 Colombia | spa |
| dc.rights.accesRights | info:eu-repo/semantics/openAccess | |
| dc.rights.acceso | Abierto (Texto Completo) | spa |
| dc.rights.licencia | EL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realizó sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la universidad actúa como un tercero de buena fe. EL AUTOR, autoriza a LA UNIVERSIDAD DEL ROSARIO, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995 y demás normas generales sobre la materia, utilice y use la obra objeto de la presente autorización. -------------------------------------- POLITICA DE TRATAMIENTO DE DATOS PERSONALES. Declaro que autorizo previa y de forma informada el tratamiento de mis datos personales por parte de LA UNIVERSIDAD DEL ROSARIO para fines académicos y en aplicación de convenios con terceros o servicios conexos con actividades propias de la academia, con estricto cumplimiento de los principios de ley. Para el correcto ejercicio de mi derecho de habeas data cuento con la cuenta de correo habeasdata@urosario.edu.co, donde previa identificación podré solicitar la consulta, corrección y supresión de mis datos. | spa |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.5/co/ | |
| dc.source.instname | instname:Universidad del Rosario | spa |
| dc.source.reponame | reponame:Repositorio Institucional EdocUR | spa |
| dc.subject | Zika virus | spa |
| dc.subject | Colombia | spa |
| dc.subject | Guillain-Barré syndrome | spa |
| dc.subject | Nerve conduction studies | spa |
| dc.subject | Electrophysiological criteria | spa |
| dc.subject | Acute inflammatory demyelinating polyneuropathy | spa |
| dc.subject | Axonal Guillain-Barré syndrome | spa |
| dc.subject.decs | Virus Zika | spa |
| dc.subject.decs | Síndrome de Guillain-Barré | spa |
| dc.subject.keyword | Zika virus | eng |
| dc.subject.keyword | electrophysiological criteria | eng |
| dc.subject.keyword | Colombia | eng |
| dc.subject.keyword | Guillain-Barré syndrome | eng |
| dc.subject.keyword | Nerve conduction studies | eng |
| dc.subject.keyword | Nerve conduction studies | eng |
| dc.subject.keyword | Electrophysiological criteria | eng |
| dc.subject.keyword | Axonal Guillain-Barré syndrome | eng |
| dc.subject.keyword | Acute inflammatory demyelinating polyneuropathy | eng |
| dc.title | Nerve conduction patterns in Guillain-Barré syndrome associated with zika virus infection in Cucuta, Colombia | spa |
| dc.type | bachelorThesis | eng |
| dc.type.hasVersion | info:eu-repo/semantics/acceptedVersion | |
| dc.type.spa | Trabajo de grado | spa |
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